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Haploid genotype - lem2delta

Genotype summary

Description
lem2delta
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
lem2 (SPAC18G6.10)LEM domain nuclear inner membrane protein Heh1/Lem2lem2deltadeletiondeletionNull

Annotation

Single locus phenotype

FYPO:0000805 - abnormal endoplasmic reticulum organization

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FYPO:0000173 - abnormal mitotic cell cycle DNA replication checkpoint

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FYPO:0000769 - abnormal nuclear envelope morphology during vegetative growth

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FYPO:0001515 - abnormal telomere tethering at nuclear periphery during vegetative growth

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FYPO:0010034 - abolished nuclear pore clustering during cellular response to hydroxyurea

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FYPO:0000941 - abolished protein localization to mitotic spindle pole body

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FYPO:0003165 - cut with abnormal chromosome segregation

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FYPO:0000278 - decreased cell population growth following spore germination

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FYPO:0006800 - decreased centromere clustering at nuclear periphery during mitotic interphase

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FYPO:0002577 - decreased chromatin binding

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FYPO:0003411 - decreased chromatin silencing at centromere inner repeat

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FYPO:0003412 - decreased chromatin silencing at centromere outer repeat

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FYPO:0002827 - decreased chromatin silencing at silent mating-type cassette

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FYPO:0004604 - decreased chromatin silencing at subtelomere

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FYPO:0000877 - decreased histone H3-K9 dimethylation at centromere during vegetative growth

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FYPO:0000878 - decreased histone H3-K9 dimethylation at centromere inner repeat during vegetative growth

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FYPO:0000888 - decreased histone H3-K9 dimethylation at centromere outer repeat during vegetative growth

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FYPO:0000708 - decreased mating efficiency

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FYPO:0006927 - decreased nucleus:cytoplasm ratio

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FYPO:0000835 - decreased protein level

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FYPO:0001324 - decreased protein level during vegetative growth

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FYPO:0002909 - decreased protein localization to chromatin during vegetative growth

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FYPO:0002339 - decreased protein localization to nuclear periphery

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FYPO:0001514 - decreased protein localization to nucleus during vegetative growth

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FYPO:0002386 - decreased protein localization to pericentric heterochromatin at centromere outer repeat region

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FYPO:0002387 - decreased protein localization to subtelomeric heterochromatin during vegetative growth

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FYPO:0002098 - decreased protein phosphorylation during cellular response to hydroxyurea

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FYPO:0001355 - decreased vegetative cell population growth

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FYPO:0005261 - increased cell population growth on galactose carbon source

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FYPO:0009094 - increased cell population growth on lysine and proline nitrogen source

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FYPO:0009098 - increased cell population growth on mannitol carbon source

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FYPO:0002980 - increased chromatin binding

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FYPO:0005371 - increased linear minichromosome loss during vegetative growth

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FYPO:0004342 - increased LTR-derived RNA level

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FYPO:0006926 - increased nucleus:cytoplasm ratio

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FYPO:0001908 - increased pre-mRNA level

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FYPO:0003009 - increased protein localization to centromere outer repeat

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FYPO:0003011 - increased protein localization to chromatin during vegetative growth

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FYPO:0002969 - increased protein localization to mitotic spindle pole body

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FYPO:0003010 - increased protein localization to subtelomeric heterochromatin during vegetative growth

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FYPO:0005917 - increased subtelomeric heterochromatin RNA level

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FYPO:0004557 - increased vegetative cell population growth

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FYPO:0006518 - loss of viability in G0

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FYPO:0000245 - loss of viability in stationary phase

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FYPO:0003166 - monoseptate vegetative cell with binucleate and anucleate compartments

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FYPO:0003086 - normal chromatin binding

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FYPO:0002336 - normal chromatin silencing at silent mating-type cassette

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FYPO:0007553 - normal G1 to G0 transition

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FYPO:0001164 - normal growth on glucose carbon source

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FYPO:0006429 - normal histone H3-K9 dimethylation at subtelomeric heterochromatin during vegetative growth

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FYPO:0001513 - normal mitotic sister chromatid segregation

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FYPO:0001380 - normal nuclear morphology during vegetative growth

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FYPO:0001221 - normal nucleus:cytoplasm ratio

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FYPO:0003627 - normal protein localization

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FYPO:0004314 - normal protein localization to CENP-A containing chromatin

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FYPO:0000838 - normal protein localization to nucleus during vegetative growth

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FYPO:0002899 - normal protein phosphorylation during cellular response to DNA damage

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FYPO:0002099 - normal protein phosphorylation during cellular response to hydroxyurea

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FYPO:0001357 - normal vegetative cell population growth

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FYPO:0006928 - nuclear membrane blebbing

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FYPO:0000772 - perforated nuclear envelope

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FYPO:0009036 - resistance to benzamidine

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FYPO:0000763 - resistance to cadmium

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FYPO:0001450 - resistance to cold

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FYPO:0009038 - resistance to egtazic acid

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FYPO:0001103 - resistance to hydrogen peroxide

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FYPO:0001583 - resistance to lithium

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FYPO:0009085 - resistance to lithium chloride and sodium dodecyl sulfate

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FYPO:0005969 - resistance to magnesium chloride

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FYPO:0009087 - resistance to magnesium chloride and sodium dodecyl sulfate

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FYPO:0009043 - resistance to potassium chloride and sodium dodecyl sulfate

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FYPO:0009089 - resistance to sodium chloride and sodium dodecyl sulfate

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FYPO:0003383 - resistance to tert-butyl hydroperoxide

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FYPO:0001034 - resistance to tunicamycin

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FYPO:0004325 - sensitive to 5-fluorouracil

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FYPO:0000104 - sensitive to cycloheximide

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FYPO:0000799 - sensitive to diamide

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FYPO:0000842 - sensitive to ethanol during vegetative growth

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FYPO:0000785 - sensitive to formamide

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FYPO:0000088 - sensitive to hydroxyurea

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FYPO:0000089 - sensitive to methyl methanesulfonate

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FYPO:0000091 - sensitive to thiabendazole

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FYPO:0003656 - sensitive to vanadate

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FYPO:0001234 - slow vegetative cell population growth

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FYPO:0002060 - viable vegetative cell population

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FYPO:0002177 - viable vegetative cell with normal cell morphology

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