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Haploid genotype - lsd1-ao(K603A,K604A aa)

Genotype summary

Description
lsd1-ao(K603A,K604A aa)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
lsd1 (SPBC146.09c)histone demethylase SWIRM1lsd1-aoK603A,K604Aamino_acid_mutationNot assayed or wild type

Annotation

Single locus phenotype

FYPO:0003085 - decreased replication fork arrest at mating-type locus

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FYPO:0004202 - decreased spliced cen-dg RNA level

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FYPO:0006299 - increased chromatin silencing at centromere outer repeat

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FYPO:0000887 - increased histone H3-K9 dimethylation at centromere outer repeat during vegetative growth

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FYPO:0006361 - increased histone H3-K9 dimethylation at subtelomeric heterochromatin during vegetative growth

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FYPO:0001387 - loss of viability at high temperature

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FYPO:0000674 - normal cell population growth at high temperature

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FYPO:0002335 - normal chromatin silencing

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FYPO:0003082 - normal genetic imprinting at mating-type locus

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FYPO:0001690 - normal growth on camptothecin

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FYPO:0001164 - normal growth on glucose carbon source

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FYPO:0000963 - normal growth on hydroxyurea

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FYPO:0000957 - normal growth on methyl methanesulfonate

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FYPO:0001357 - normal vegetative cell population growth

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FYPO:0000091 - sensitive to thiabendazole

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