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Haploid genotype - lsd1delta

Genotype summary

Description
lsd1delta
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
lsd1 (SPBC146.09c)histone demethylase SWIRM1lsd1deltadeletiondeletionNull

Annotation

Single locus phenotype

FYPO:0004481 - abolished cell population growth at high temperature

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FYPO:0003080 - abolished genetic imprinting at mating-type locus

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FYPO:0001326 - altered RNA level during vegetative growth

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FYPO:0000251 - decreased cell population growth on galactose carbon source

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FYPO:0000888 - decreased histone H3-K9 dimethylation at centromere outer repeat during vegetative growth

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FYPO:0007505 - decreased protein localization to chromatin at promoter

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FYPO:0002387 - decreased protein localization to subtelomeric heterochromatin during vegetative growth

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FYPO:0003085 - decreased replication fork arrest at mating-type locus

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FYPO:0003090 - decreased replication fork arrest at rDNA repeats

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FYPO:0001117 - decreased RNA level during vegetative growth

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FYPO:0001355 - decreased vegetative cell population growth

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FYPO:0000636 - increased cell population growth rate

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FYPO:0000220 - increased centromeric outer repeat transcript level

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FYPO:0005225 - increased histone H3-K4 dimethylation during vegetative growth

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FYPO:0000875 - increased histone H3-K9 dimethylation at centromere inner repeat during vegetative growth

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FYPO:0000873 - increased histone H3-K9 dimethylation during vegetative growth

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FYPO:0000881 - increased histone H3-K9 trimethylation at centromere inner repeat during vegetative growth

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FYPO:0007507 - increased histone H3-K9 trimethylation at promoter during vegetative growth

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FYPO:0007509 - increased histone H3-K9 trimethylation at silent mating-type cassette during vegetative growth

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FYPO:0007508 - increased histone H3-K9 trimethylation at subtelomeric heterochromatin during vegetative growth

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FYPO:0007506 - increased protein localization to chromatin at promoter

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FYPO:0004377 - increased protein localization to heterochromatin at silent mating-type cassette

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FYPO:0003010 - increased protein localization to subtelomeric heterochromatin during vegetative growth

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FYPO:0000825 - increased RNA level during vegetative growth

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FYPO:0004948 - increased spatial extent of centromeric heterochromatin assembly

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FYPO:0002837 - normal centromeric outer repeat transcript-derived siRNA level

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FYPO:0004325 - sensitive to 5-fluorouracil

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FYPO:0002642 - sensitive to amphotericin B

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FYPO:0002640 - sensitive to clotrimazole

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FYPO:0002641 - sensitive to micafungin

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FYPO:0002328 - sensitive to terbinafine

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FYPO:0002060 - viable vegetative cell population

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FYPO:0002197 - viable vegetative cell with abnormal cell shape

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FYPO:0001510 - viable vegetative cell, abnormal cell shape, normal cell size

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