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Haploid genotype - lsd2-deltaC(1165-1235 Δaa)[Knockdown] sir2delta

Genotype summary

Description
lsd2-deltaC(1165-1235 Δaa)[Knockdown] sir2delta
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
lsd2 (SPAC23E2.02)histone demethylase SWIRM2lsd2-deltaC1165-1235partial_amino_acid_deletionKnockdown
sir2 (SPBC16D10.07c)histone deacetylase, Sirtuin family, NAD-dependent Sir2sir2deltadeletiondeletionNull

Annotation

Multi-locus phenotype

FYPO:0000082 - decreased cell population growth at high temperature

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FYPO:0003412 - decreased chromatin silencing at centromere outer repeat

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FYPO:0002827 - decreased chromatin silencing at silent mating-type cassette

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FYPO:0005922 - decreased heterochromatin assembly at subtelomere

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FYPO:0000888 - decreased histone H3-K9 dimethylation at centromere outer repeat during vegetative growth

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FYPO:0002355 - decreased histone H3-K9 dimethylation at silent mating-type cassette during vegetative growth

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FYPO:0004137 - decreased histone H3-K9 dimethylation at subtelomeric heterochromatin during vegetative growth

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FYPO:0007339 - increased cen-dg RNA level

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FYPO:0006110 - increased silent mating-type cassette transcript-derived siRNA level

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FYPO:0005917 - increased subtelomeric heterochromatin RNA level

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