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Haploid genotype - mad1-KAKA(K24A,K25A aa)

Genotype summary

Description
mad1-KAKA(K24A,K25A aa)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
mad1 (SPBC3D6.04c)Mad2 receptor at unattached kinetochores, Mad1mad1-KAKAK24A,K25Aamino_acid_mutationNot assayed or wild type

Annotation

Single locus phenotype

FYPO:0000030 - abnormal mitotic chromosome congression

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FYPO:0008164 - abnormal protein localization to kinetochore during mitotic M phase

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FYPO:0000705 - abolished protein-protein interaction

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FYPO:0005211 - decreased protein localization to mitotic spindle pole body during anaphase

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FYPO:0003762 - normal mitotic spindle assembly checkpoint

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FYPO:0005212 - normal protein localization to kinetochore during mitotic prometaphase

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FYPO:0002901 - normal protein localization to kinetochore during vegetative growth

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FYPO:0002563 - normal protein localization to nuclear periphery

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FYPO:0000091 - sensitive to thiabendazole

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FYPO:0005069 - unequal mitotic sister chromatid segregation following normal mitosis

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