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Haploid genotype - mcm2-2a(Y80A,Y89A aa)

Genotype summary

Description
mcm2-2a(Y80A,Y89A aa)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
mcm2 (SPBC4.04c)MCM complex subunit Mcm2mcm2-2aY80A,Y89Aamino_acid_mutationNot assayed or wild type

Annotation

Single locus phenotype

FYPO:0007376 - abolished epigenetic heterochromatin inheritance

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FYPO:0003217 - decreased chromatin silencing at centromere central core

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FYPO:0003412 - decreased chromatin silencing at centromere outer repeat

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FYPO:0007478 - decreased epigenetic heterochromatin inheritance

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FYPO:0008185 - decreased histone H3-K9 trimethylation at centromere central core during vegetative growth

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FYPO:0000890 - decreased histone H3-K9 trimethylation at centromere outer repeat during vegetative growth

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FYPO:0005845 - decreased histone H3-K9 trimethylation at silent mating-type cassette during vegetative growth

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