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Haploid genotype - mcm4-tstd(Ub-DHFRts-mcm4)

Genotype summary

Description
mcm4-tstd(Ub-DHFRts-mcm4)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
mcm4 (SPCC16A11.17)MCM complex subunit Mcm4/Cdc21mcm4-tstdUb-DHFRts-mcm4fusion_or_chimeraNot assayed or wild type

Annotation

Single locus phenotype

FYPO:0000611 - abnormal cell cycle arrest in mitotic S phase

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FYPO:0001430 - abnormal mitotic cell cycle arrest with unreplicated DNA

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FYPO:0001680 - abolished protein localization to chromatin during premeiotic DNA replication

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FYPO:0001681 - abolished protein localization to chromatin during S phase of meiotic cell cycle

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FYPO:0001270 - complete but unequal mitotic sister chromatid segregation

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FYPO:0000229 - cut

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FYPO:0003165 - cut with abnormal chromosome segregation

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FYPO:0000476 - decreased frequency of meiosis

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FYPO:0000835 - decreased protein level

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FYPO:0002993 - decreased protein phosphorylation during cellular response to methyl methanesulfonate

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FYPO:0001740 - increased gross chromosomal rearrangement

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FYPO:0001840 - increased minichromosome loss during vegetative growth

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FYPO:0005068 - increased number of double-strand break sites during mitotic S phase

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FYPO:0000455 - increased number of double-strand break sites during vegetative growth

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FYPO:0001387 - loss of viability at high temperature

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FYPO:0000833 - normal protein level during vegetative growth

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FYPO:0007381 - Ssb1 megafocus present

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