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Haploid genotype - mde4-12A(S147A,S242A,S247A,S252A,S270A,T275A,S290A,S295A,S316A,S349A,S354A,S401A aa)

Genotype summary

Description
mde4-12A(S147A,S242A,S247A,S252A,S270A,T275A,S290A,S295A,S316A,S349A,S354A,S401A aa)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
mde4 (SPBC6B1.04)microtubule-site clamp monopolin complex subunit Mde4mde4-12AS147A,S242A,S247A,S252A,S270A,T275A,S290A,S295A,S316A,S349A,S354A,S401Aamino_acid_mutationNot assayed or wild type

Annotation

Single locus phenotype

FYPO:0000705 - abolished protein-protein interaction

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FYPO:0004449 - decreased protein phosphorylation during mitotic metaphase

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FYPO:0002636 - delayed onset of mitotic spindle elongation

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FYPO:0000228 - lagging mitotic chromosomes

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FYPO:0002901 - normal protein localization to kinetochore during vegetative growth

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FYPO:0004383 - premature protein localization to mitotic spindle

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