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Haploid genotype - mis12-537(G52E aa)

Genotype summary

Description
mis12-537(G52E aa)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
mis12 (SPBC409.04c)MIS12/MIND complex Mis12mis12-537G52Eamino_acid_mutationNot assayed or wild type

Annotation

Single locus phenotype

FYPO:0004308 - abnormal CENP-A containing chromatin organization

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FYPO:0004481 - abolished cell population growth at high temperature

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FYPO:0001269 - abolished protein localization to kinetochore during vegetative growth

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FYPO:0000082 - decreased cell population growth at high temperature

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FYPO:0002902 - decreased protein localization to kinetochore during vegetative growth

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FYPO:0001837 - increased duration of protein localization to mitotic spindle pole body

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FYPO:0000786 - increased plasmid loss

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FYPO:0002061 - inviable vegetative cell population

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FYPO:0006715 - large and small daughter nuclei

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FYPO:0000284 - large and small daughter nuclei, with unequal mitotic sister chromatid segregation

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FYPO:0006190 - long mitotic spindle during anaphase A

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FYPO:0003787 - long mitotic spindle microtubules protruding beyond spindle pole body

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FYPO:0001387 - loss of viability at high temperature

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FYPO:0002141 - normal cell population growth at low temperature

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FYPO:0002360 - normal chromatin silencing at centromere

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FYPO:0001164 - normal growth on glucose carbon source

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FYPO:0000964 - normal growth on thiabendazole

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FYPO:0004314 - normal protein localization to CENP-A containing chromatin

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FYPO:0008025 - normal protein localization to CENP-A containing chromatin during mitosis

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FYPO:0007234 - normal protein localization to centromere central core

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FYPO:0002574 - normal protein localization to centromere during vegetative growth

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FYPO:0002901 - normal protein localization to kinetochore during vegetative growth

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FYPO:0003788 - nuclear envelope protrusion present during mitosis

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FYPO:0000678 - unequal homologous chromosome segregation

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FYPO:0003241 - unequal mitotic sister chromatid segregation

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