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Haploid genotype - mis15-68(W113R aa)

Genotype summary

Description
mis15-68(W113R aa)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
mis15 (SPBP22H7.09c)CENP-N ortholog Mis15mis15-68W113Ramino_acid_mutationNot assayed or wild type

Annotation

Single locus phenotype

FYPO:0000141 - abnormal mitotic sister chromatid segregation

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FYPO:0000082 - decreased cell population growth at high temperature

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FYPO:0003740 - decreased CENP-A containing chromatin assembly

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FYPO:0003217 - decreased chromatin silencing at centromere central core

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FYPO:0008014 - decreased protein localization to CENP-A containing chromatin during mitosis

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FYPO:0002902 - decreased protein localization to kinetochore during vegetative growth

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FYPO:0007295 - increased protein localization to CENP-A containing chromatin

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FYPO:0000284 - large and small daughter nuclei, with unequal mitotic sister chromatid segregation

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FYPO:0007234 - normal protein localization to centromere central core

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FYPO:0000091 - sensitive to thiabendazole

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