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Haploid genotype - mis4-242(G1326E aa)

Genotype summary

Description
mis4-242(G1326E aa)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
mis4 (SPAC31A2.05c)cohesin loading factor (adherin) Mis4/Scc2mis4-242G1326Eamino_acid_mutationNot assayed or wild type

Annotation

Single locus phenotype

FYPO:0000619 - abnormal cell cycle arrest in mitotic anaphase

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FYPO:0000620 - abnormal cell cycle arrest in mitotic metaphase

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FYPO:0000611 - abnormal cell cycle arrest in mitotic S phase

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FYPO:0001127 - abnormal cell size

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FYPO:0004308 - abnormal CENP-A containing chromatin organization

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FYPO:0006174 - abolished mitotic spindle elongation during anaphase B

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FYPO:0001269 - abolished protein localization to kinetochore during vegetative growth

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FYPO:0004412 - abolished protein localization to mitotic spindle midzone during anaphase

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FYPO:0004832 - abolished protein localization to mitotic spindle midzone during anaphase A

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FYPO:0000082 - decreased cell population growth at high temperature

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FYPO:0005555 - decreased mitotic cohesin loading

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FYPO:0002797 - decreased protein degradation

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FYPO:0004833 - decreased protein localization to mitotic spindle midzone during anaphase B

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FYPO:0001355 - decreased vegetative cell population growth

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FYPO:0000639 - delayed onset of septum assembly

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FYPO:0002638 - increased activation of mitotic spindle assembly checkpoint

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FYPO:0000274 - increased duration of mitotic M phase

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FYPO:0001707 - increased mitotic DNA damage checkpoint activation

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FYPO:0003307 - increased mitotic index

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FYPO:0000786 - increased plasmid loss

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FYPO:0005735 - increased protein localization to kinetochore during mitotic M phase

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FYPO:0000839 - inviable elongated mononucleate aseptate cell

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FYPO:0002090 - lagging chromosomes

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FYPO:0000228 - lagging mitotic chromosomes

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FYPO:0004307 - long mitotic spindle during metaphase

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FYPO:0005345 - mitotic sister chromatid separation during interphase

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FYPO:0007914 - mitotic sister chromatid separation during metaphase

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FYPO:0002141 - normal cell population growth at low temperature

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FYPO:0001532 - normal duration of mitotic S phase

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FYPO:0002102 - normal mitotic DNA damage checkpoint during cellular response to UV

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FYPO:0000088 - sensitive to hydroxyurea

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FYPO:0000091 - sensitive to thiabendazole

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FYPO:0007304 - short bipolar mitotic spindle during anaphase

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FYPO:0003241 - unequal mitotic sister chromatid segregation

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FYPO:0005069 - unequal mitotic sister chromatid segregation following normal mitosis

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