Haploid genotype - mkt1delta sir2delta

Genotype summary

Description: mkt1delta sir2delta
Organism: Schizosaccharomyces pombe (fission yeast)

Allele summary

gene	Product	Allele name	Description	Type	Expression
mkt1 (SPAC139.01c)	post-transcriptional RNA stability regulator Mkt1	mkt1delta	deletion	deletion	Null
sir2 (SPBC16D10.07c)	histone deacetylase, Sirtuin family, NAD-dependent Sir2	sir2delta	deletion	deletion	Null

Annotation

Multi-locus phenotype

FYPO:0003412 - decreased chromatin silencing at centromere outer repeat

References:

PMID:31822915

Genes:

FYPO:0000888 - decreased histone H3-K9 dimethylation at centromere outer repeat during vegetative growth

References:

PMID:31822915

Genes:

FYPO:0002836 - increased centromeric outer repeat transcript-derived siRNA level

References:

PMID:31822915

Genes:

FYPO:0007227 - increased number of R-loops at centromere

References:

PMID:31822915

Genes: