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Haploid genotype - mmi1delta

Genotype summary

Description
mmi1delta
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
mmi1 (SPCC736.12c)nucleur exosome adaptor Mmi1mmi1deltadeletiondeletionNull

Annotation

Single locus phenotype

FYPO:0008155 - abnormal regulatory lncRNA 3'-end processing

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FYPO:0004851 - abnormal RNA metabolic process

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FYPO:0004811 - abnormal termination of RNA polymerase II transcription

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FYPO:0005861 - abolished CCR4-NOT complex binding

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FYPO:0007530 - abolished histone H3-K9 dimethylation at heterochromatin island at meiotic gene during vegetative growth

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FYPO:0005862 - abolished MTREC complex binding

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FYPO:0007215 - abolished protein localization to chromatin at lncRNA gene

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FYPO:0007214 - abolished protein localization to heterochromatin island

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FYPO:0001045 - decreased acid phosphatase activity

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FYPO:0000303 - decreased conjugation frequency

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FYPO:0006269 - decreased histone H3-K9 dimethylation at protein coding gene during vegetative growth

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FYPO:0003230 - decreased histone H3-K9 methylation at heterochromatin island during vegetative growth

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FYPO:0000708 - decreased mating efficiency

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FYPO:0006612 - decreased protein localization to chromatin at transcription termination site

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FYPO:0007280 - decreased protein localization to nuclear exosome focus

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FYPO:0000826 - decreased RNA level

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FYPO:0000584 - decreased sporulation frequency

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FYPO:0002960 - increased level of DSR-containing meiotic gene mRNA during vegetative growth

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FYPO:0002173 - increased level of meiotic gene mRNA during vegetative growth

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FYPO:0000836 - increased protein level

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FYPO:0001327 - increased protein level during vegetative growth

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FYPO:0000825 - increased RNA level during vegetative growth

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FYPO:0000316 - inviable after spore germination

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FYPO:0002148 - inviable after spore germination, multiple cell divisions, abnormal morphology

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FYPO:0002061 - inviable vegetative cell population

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FYPO:0005863 - loss of punctate nuclear protein localization

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FYPO:0006996 - normal antisense RNA level

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FYPO:0002336 - normal chromatin silencing at silent mating-type cassette

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FYPO:0000833 - normal protein level during vegetative growth

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FYPO:0002357 - normal protein-RNA interaction

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FYPO:0001317 - normal RNA level during vegetative growth

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FYPO:0002085 - normal vegetative cell growth

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