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Diploid genotype - moa1delta/moa1delta

Genotype summary

Description
moa1delta/moa1delta
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

locus Product Allele name Description Type Expression
moa1 (SPAC15E1.07c)meiosis specific kinetochore regulator (Meikin) Moa1moa1deltadeletiondeletionNull
moa1deltadeletiondeletionNull

Annotation

Single locus phenotype

FYPO:0000151 - abnormal meiotic chromosome segregation

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FYPO:0001894 - abnormal sporulation resulting in formation of ascus with more or fewer than four spores

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FYPO:0006424 - abolished meiotic sister chromatid cohesion at centromere during meiosis I

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FYPO:0000460 - decreased mitotic centromeric sister chromatid cohesion

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FYPO:0007295 - increased protein localization to CENP-A containing chromatin

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FYPO:0008190 - increased protein localization to chromatin at centromere central core during meiotic prophase I

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FYPO:0008192 - increased protein localization to pericentric heterochromatin during meiotic prophase I

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FYPO:0002151 - inviable spore

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FYPO:0000488 - normal meiotic recombination

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FYPO:0004314 - normal protein localization to CENP-A containing chromatin

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FYPO:0008193 - normal protein localization to pericentric heterochromatin during meiotic prophase I

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FYPO:0003182 - sister chromatid nondisjunction at meiosis II

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FYPO:0005648 - sister kinetochore dissociation in meiotic metaphase I

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FYPO:0005634 - sister kinetochore dissociation in meiotic metaphase I with equational sister chromatid segregation in meiosis I

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FYPO:0005633 - sister kinetochore dissociation in meiotic metaphase I, normal chromosome segregation in meiosis I, and sister chromatid non-disjunction in meiosis II

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