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Haploid genotype - mot2delta

Genotype summary

Description
mot2delta
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
mot2 (SPAC16C9.04c)CCR4-Not complex ubiquitin-protein ligase E3 subunit 4mot2deltadeletiondeletionNull

Annotation

Single locus phenotype

FYPO:0007336 - abolished chromatin silencing at silent mating-type cassette

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FYPO:0006993 - decreased chromatin silencing at centromere otr1R

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FYPO:0004604 - decreased chromatin silencing at subtelomere

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FYPO:0002355 - decreased histone H3-K9 dimethylation at silent mating-type cassette during vegetative growth

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FYPO:0004137 - decreased histone H3-K9 dimethylation at subtelomeric heterochromatin during vegetative growth

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FYPO:0005845 - decreased histone H3-K9 trimethylation at silent mating-type cassette during vegetative growth

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FYPO:0003573 - decreased protein localization to heterochromatin at silent mating-type cassette

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FYPO:0002768 - decreased protein ubiquitination during vegetative growth

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FYPO:0007891 - decreased spatial extent of mating-type region heterochromatin assembly

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FYPO:0007480 - decreased spatial extent of subtelomeric heterochromatin assembly

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FYPO:0001355 - decreased vegetative cell population growth

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FYPO:0009094 - increased cell population growth on lysine and proline nitrogen source

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FYPO:0009093 - increased cell population growth on lysine and serine nitrogen source

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FYPO:0009072 - increased cell population growth on lysine nitrogen source

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FYPO:0002960 - increased level of DSR-containing meiotic gene mRNA during vegetative growth

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FYPO:0002173 - increased level of meiotic gene mRNA during vegetative growth

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FYPO:0001327 - increased protein level during vegetative growth

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FYPO:0004377 - increased protein localization to heterochromatin at silent mating-type cassette

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FYPO:0006518 - loss of viability in G0

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FYPO:0006992 - normal chromatin silencing at centromere otr1R

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FYPO:0005993 - normal cytoplasmic translation

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FYPO:0007553 - normal G1 to G0 transition

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FYPO:0004083 - normal protein level

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FYPO:0004378 - normal protein localization to heterochromatin at silent mating-type cassette

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FYPO:0001317 - normal RNA level during vegetative growth

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FYPO:0009038 - resistance to egtazic acid

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FYPO:0001583 - resistance to lithium

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FYPO:0009087 - resistance to magnesium chloride and sodium dodecyl sulfate

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FYPO:0000725 - resistance to methyl methanesulfonate

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FYPO:0009043 - resistance to potassium chloride and sodium dodecyl sulfate

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FYPO:0003383 - resistance to tert-butyl hydroperoxide

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FYPO:0000785 - sensitive to formamide

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FYPO:0000087 - sensitive to hydrogen peroxide

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FYPO:0009071 - sensitive to itraconazole

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FYPO:0003656 - sensitive to vanadate

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FYPO:0002060 - viable vegetative cell population

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FYPO:0002177 - viable vegetative cell with normal cell morphology

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