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Haploid genotype - mph1-kd(D459A aa)

Genotype summary

Description
mph1-kd(D459A aa)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
mph1 (SPBC106.01)dual specificity protein kinase Mph1mph1-kdD459Aamino_acid_mutationNot assayed or wild type

Annotation

Single locus phenotype

FYPO:0000620 - abnormal cell cycle arrest in mitotic metaphase

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FYPO:0000141 - abnormal mitotic sister chromatid segregation

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FYPO:0001384 - abolished protein kinase activity

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FYPO:0001269 - abolished protein localization to kinetochore during vegetative growth

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FYPO:0002678 - abolished protein phosphorylation

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FYPO:0005781 - decreased duration of mitotic spindle assembly checkpoint

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FYPO:0005782 - decreased mitotic checkpoint complex level

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FYPO:0004156 - decreased protein level during mitosis

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FYPO:0004357 - decreased protein phosphorylation during mitosis

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FYPO:0001645 - decreased protein-protein interaction

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FYPO:0002638 - increased activation of mitotic spindle assembly checkpoint

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FYPO:0001840 - increased minichromosome loss during vegetative growth

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FYPO:0004310 - normal duration of mitotic M phase

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FYPO:0000703 - normal protein-protein interaction

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FYPO:0000094 - sensitive to benomyl

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FYPO:0001234 - slow vegetative cell population growth

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