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Haploid genotype - mrc1-6A(S599A,S604A,S614A,T634A,S637A,T645A aa)

Genotype summary

Description
mrc1-6A(S599A,S604A,S614A,T634A,S637A,T645A aa)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
mrc1 (SPAC694.06c)checkpoint signalling adaptor, claspin, Mrc1mrc1-6AS599A,S604A,S614A,T634A,S637A,T645Aamino_acid_mutationNot assayed or wild type

Annotation

Single locus phenotype

FYPO:0004550 - abolished protein phosphorylation during cellular response to hydroxyurea

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FYPO:0001382 - decreased protein kinase activity

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FYPO:0001929 - normal cell cycle regulation during cellular response to hydroxyurea

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FYPO:0007479 - normal epigenetic heterochromatin inheritance

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FYPO:0003075 - normal protein kinase activity

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FYPO:0004962 - normal protein localization to chromatin at replication origin

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FYPO:0000088 - sensitive to hydroxyurea

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