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Haploid genotype - mrc1-K235E,K236E(aa)

Genotype summary

Description
mrc1-K235E,K236E(aa)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
mrc1 (SPAC694.06c)checkpoint signalling adaptor, claspin, Mrc1mrc1-K235E,K236EK235E,K236Eamino_acid_mutationNot assayed or wild type

Annotation

Single locus phenotype

FYPO:0006555 - abnormal multiple protein binding to DNA

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FYPO:0000659 - abolished DNA binding

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FYPO:0000705 - abolished protein-protein interaction

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FYPO:0003165 - cut with abnormal chromosome segregation

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FYPO:0003081 - decreased genetic imprinting at mating-type locus

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FYPO:0006602 - decreased replication fork arrest at MPS1 barrier

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FYPO:0000584 - decreased sporulation frequency

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FYPO:0006605 - normal S-phase DNA damage checkpoint during cellular response to methyl methanesulfonate

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FYPO:0000088 - sensitive to hydroxyurea

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