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Haploid genotype - mre11-D65N(aa)

Genotype summary

Description
mre11-D65N(aa)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
mre11 (SPAC13C5.07)Mre11 nucleasemre11-D65ND65Namino_acid_mutationNot assayed or wild type

Annotation

Single locus phenotype

FYPO:0005268 - abnormal mitotic cell cycle regulation during cellular response to methyl methanesulfonate

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FYPO:0000006 - abnormal mitotic DNA damage checkpoint

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FYPO:0001118 - abnormal vegetative cell morphology

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FYPO:0001382 - decreased protein kinase activity

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FYPO:0004261 - decreased protein phosphorylation during mitotic G2 phase during cellular response to ionizing radiation

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FYPO:0001355 - decreased vegetative cell population growth

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FYPO:0000657 - increased DNA binding

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FYPO:0001489 - inviable vegetative cell

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FYPO:0004286 - normal double-strand break repair via nonhomologous end joining

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FYPO:0006319 - normal extent of DNA resection during replication fork processing

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FYPO:0005954 - normal histone H2A phosphorylation during cellular response to ionizing radiation

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FYPO:0005236 - normal protein localization to chromatin at stalled replication fork

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FYPO:0004252 - normal regulation of DNA replication during replication fork arrest

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FYPO:0003503 - normal vegetative cell length

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FYPO:0005549 - normal viability upon nitrogen starvation

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FYPO:0000085 - sensitive to camptothecin

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FYPO:0000088 - sensitive to hydroxyurea

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FYPO:0000267 - sensitive to ionizing radiation during vegetative growth

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FYPO:0000089 - sensitive to methyl methanesulfonate

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FYPO:0005919 - sensitive to TOP-53

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FYPO:0000268 - sensitive to UV during vegetative growth

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FYPO:0001234 - slow vegetative cell population growth

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FYPO:0000646 - swollen vegetative cell

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