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Haploid genotype - mre11-W248R(aa)

Genotype summary

Description
mre11-W248R(aa)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
mre11 (SPAC13C5.07)Mre11 nucleasemre11-W248RW248Ramino_acid_mutationNot assayed or wild type

Annotation

Single locus phenotype

FYPO:0000121 - abnormal sporulation

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FYPO:0001407 - decreased cell population growth on glucose carbon source

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FYPO:0000218 - decreased Mre11 complex assembly

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FYPO:0001324 - decreased protein level during vegetative growth

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FYPO:0002474 - decreased protein localization to double-strand break site

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FYPO:0002470 - decreased protein phosphorylation during cellular response to ionizing radiation

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FYPO:0001645 - decreased protein-protein interaction

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FYPO:0000972 - increased number of Rad52 foci during vegetative growth

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FYPO:0002475 - increased protein localization to double-strand break site

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FYPO:0000085 - sensitive to camptothecin

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FYPO:0000266 - sensitive to DNA damaging agents

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FYPO:0000088 - sensitive to hydroxyurea

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FYPO:0000267 - sensitive to ionizing radiation during vegetative growth

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FYPO:0000089 - sensitive to methyl methanesulfonate

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FYPO:0000268 - sensitive to UV during vegetative growth

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FYPO:0001492 - viable elongated vegetative cell

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