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Haploid genotype - mre11delta

Genotype summary

Description
mre11delta
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
mre11 (SPAC13C5.07)Mre11 nucleasemre11deltadeletiondeletionNull

Annotation

Single locus phenotype

FYPO:0001352 - abnormal chromatin organization during vegetative growth

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FYPO:0003661 - abnormal double-strand break repair via nonhomologous end joining

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FYPO:0003625 - abnormal microtubule cytoskeleton morphology during mitotic interphase

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FYPO:0000059 - abnormal mitotic cell cycle

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FYPO:0005268 - abnormal mitotic cell cycle regulation during cellular response to methyl methanesulfonate

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FYPO:0000006 - abnormal mitotic DNA damage checkpoint

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FYPO:0000913 - abnormal sporulation resulting in formation of ascus containing non-uniform spores

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FYPO:0001118 - abnormal vegetative cell morphology

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FYPO:0005453 - abolished break-induced loss of heterozygosity via chromosomal translocation

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FYPO:0005140 - abolished meiotic recombination double-strand break repair

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FYPO:0003486 - abolished protein localization to double-strand break site

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FYPO:0005616 - abolished protein phosphorylation during cellular response to bleomycin

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FYPO:0000705 - abolished protein-protein interaction

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FYPO:0005451 - decreased break-induced loss of heterozygosity

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FYPO:0000278 - decreased cell population growth following spore germination

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FYPO:0001407 - decreased cell population growth on glucose carbon source

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FYPO:0009091 - decreased cell population growth on lysine and proline nitrogen source

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FYPO:0002924 - decreased cell population growth on maltose carbon source

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FYPO:0001176 - decreased cell population growth on sucrose carbon source

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FYPO:0006687 - decreased DNA double-strand break processing during double-strand break repair via homologous recombination

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FYPO:0003660 - decreased double-strand break repair during vegetative growth

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FYPO:0003912 - decreased double-strand break repair via homologous recombination

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FYPO:0004287 - decreased double-strand break repair via nonhomologous end joining

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FYPO:0005408 - decreased duration of mitotic S phase during cellular response to methyl methanesulfonate

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FYPO:0000185 - decreased gene conversion during vegetative growth

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FYPO:0000708 - decreased mating efficiency

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FYPO:0000470 - decreased mating type switching

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FYPO:0001382 - decreased protein kinase activity

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FYPO:0001324 - decreased protein level during vegetative growth

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FYPO:0002474 - decreased protein localization to double-strand break site

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FYPO:0002470 - decreased protein phosphorylation during cellular response to ionizing radiation

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FYPO:0000581 - decreased spore germination frequency

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FYPO:0000584 - decreased sporulation frequency

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FYPO:0001355 - decreased vegetative cell population growth

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FYPO:0001122 - elongated vegetative cell

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FYPO:0005452 - increased break-induced loss of heterozygosity

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FYPO:0005261 - increased cell population growth on galactose carbon source

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FYPO:0003004 - increased cellular reactive oxygen species level during vegetative growth

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FYPO:0005618 - increased duration of meiotic recombination double-strand break repair

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FYPO:0003662 - increased error-free double-strand break repair

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FYPO:0007392 - increased loss of disomic chromosome 3

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FYPO:0001840 - increased minichromosome loss during vegetative growth

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FYPO:0000972 - increased number of Rad52 foci during vegetative growth

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FYPO:0002475 - increased protein localization to double-strand break site

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FYPO:0004557 - increased vegetative cell population growth

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FYPO:0002150 - inviable spore population

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FYPO:0001489 - inviable vegetative cell

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FYPO:0006518 - loss of viability in G0

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FYPO:0000245 - loss of viability in stationary phase

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FYPO:0001927 - normal cell cycle regulation during cellular response to ionizing radiation

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FYPO:0003555 - normal chromatin silencing at subtelomere

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FYPO:0004286 - normal double-strand break repair via nonhomologous end joining

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FYPO:0007553 - normal G1 to G0 transition

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FYPO:0007035 - normal growth on 5-fluorouracil

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FYPO:0005136 - normal meiotic DNA double-strand break formation

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FYPO:0005299 - normal mitotic G2 DNA damage checkpoint during cellular response to UV

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FYPO:0002554 - normal protein localization to double-strand break site

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FYPO:0002687 - normal telomere length during vegetative growth

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FYPO:0002693 - resistance to diamide

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FYPO:0009085 - resistance to lithium chloride and sodium dodecyl sulfate

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FYPO:0000077 - resistance to rapamycin

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FYPO:0000327 - resistance to trichostatin A

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FYPO:0007933 - sensitive to 2,2′-dipyridyl

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FYPO:0001098 - sensitive to 4-nitroquinoline N-oxide

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FYPO:0001097 - sensitive to amitrole

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FYPO:0009067 - sensitive to amorolfine

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FYPO:0000095 - sensitive to bleomycin

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FYPO:0000098 - sensitive to calcium

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FYPO:0000085 - sensitive to camptothecin

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FYPO:0000102 - sensitive to cisplatin

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FYPO:0001245 - sensitive to cobalt

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FYPO:0000104 - sensitive to cycloheximide

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FYPO:0000799 - sensitive to diamide

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FYPO:0003559 - sensitive to doxorubicin

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FYPO:0007931 - sensitive to egtazic acid

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FYPO:0000842 - sensitive to ethanol during vegetative growth

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FYPO:0007928 - sensitive to ethylenediaminetetraacetic acid

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FYPO:0003858 - sensitive to etoposide

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FYPO:0000785 - sensitive to formamide

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FYPO:0000087 - sensitive to hydrogen peroxide

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FYPO:0000088 - sensitive to hydroxyurea

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FYPO:0000267 - sensitive to ionizing radiation during vegetative growth

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FYPO:0009071 - sensitive to itraconazole

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FYPO:0009086 - sensitive to lithium chloride and sodium dodecyl sulfate

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FYPO:0006836 - sensitive to magnesium chloride

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FYPO:0009088 - sensitive to magnesium chloride and sodium dodecyl sulfate

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FYPO:0000089 - sensitive to methyl methanesulfonate

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FYPO:0001214 - sensitive to potassium chloride

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FYPO:0009082 - sensitive to potassium chloride and methyl methanesulfonate

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FYPO:0007924 - sensitive to potassium chloride and sodium dodecyl sulfate

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FYPO:0005889 - sensitive to sodium chloride

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FYPO:0000797 - sensitive to tert-butyl hydroperoxide

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FYPO:0000091 - sensitive to thiabendazole

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FYPO:0001457 - sensitive to tunicamycin

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FYPO:0005624 - sensitive to UV during mitotic S phase

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FYPO:0000268 - sensitive to UV during vegetative growth

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FYPO:0000115 - sensitive to valproic acid

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FYPO:0003656 - sensitive to vanadate

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FYPO:0002239 - shortened telomeres during vegetative growth

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FYPO:0001234 - slow vegetative cell population growth

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FYPO:0005455 - telomere assembly at double-strand break site

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FYPO:0001492 - viable elongated vegetative cell

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FYPO:0003612 - viable spore population

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FYPO:0001491 - viable vegetative cell

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FYPO:0002060 - viable vegetative cell population

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FYPO:0002197 - viable vegetative cell with abnormal cell shape

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