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Haploid genotype - mtl1-1(I522M,L543P,Y551H,L557P,D793G,A998V aa)

Genotype summary

Description
mtl1-1(I522M,L543P,Y551H,L557P,D793G,A998V aa)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
mtl1 (SPAC17H9.02)MTREC (exosome adaptor) complex RNA helicase subunit Mtl1mtl1-1I522M,L543P,Y551H,L557P,D793G,A998Vamino_acid_mutationNot assayed or wild type

Annotation

Single locus phenotype

FYPO:0003230 - decreased histone H3-K9 methylation at heterochromatin island during vegetative growth

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FYPO:0002173 - increased level of meiotic gene mRNA during vegetative growth

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FYPO:0002931 - increased poly(A) tail length

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FYPO:0001908 - increased pre-mRNA level

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FYPO:0000825 - increased RNA level during vegetative growth

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FYPO:0003237 - increased RNA splicing at cryptic splice sites

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FYPO:0002916 - increased RNA splicing, via spliceosome

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FYPO:0003235 - normal histone H3-K9 methylation at centromere outer repeat during vegetative growth

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FYPO:0002239 - shortened telomeres during vegetative growth

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