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Haploid genotype - nbs1-RKAA(R27A,K45A aa)

Genotype summary

Description
nbs1-RKAA(R27A,K45A aa)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
nbs1 (SPBC6B1.09c)Mre11 complex BRCT domain subunit Nbs1nbs1-RKAAR27A,K45Aamino_acid_mutationNot assayed or wild type

Annotation

Single locus phenotype

FYPO:0000705 - abolished protein-protein interaction

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FYPO:0002474 - decreased protein localization to double-strand break site

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FYPO:0002554 - normal protein localization to double-strand break site

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FYPO:0000085 - sensitive to camptothecin

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FYPO:0000088 - sensitive to hydroxyurea

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FYPO:0000267 - sensitive to ionizing radiation during vegetative growth

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