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Haploid genotype - nbs1-c60-delta(554-613 Δaa) rad3(1-1476)(1477-2386 Δaa)

Genotype summary

Description
nbs1-c60-delta(554-613 Δaa) rad3(1-1476)(1477-2386 Δaa)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
nbs1 (SPBC6B1.09c)Mre11 complex BRCT domain subunit Nbs1nbs1-c60-delta554-613partial_amino_acid_deletionNot assayed or wild type
rad3 (SPBC216.05)ATR checkpoint kinase Rad3rad3(1-1476)1477-2386partial_amino_acid_deletionNot assayed or wild type

Annotation

Multi-locus phenotype

FYPO:0004867 - decreased histone H2A phosphorylation during cellular response to ionizing radiation

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FYPO:0004656 - increased protein localization to telomere during vegetative growth

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FYPO:0002887 - normal protein localization to telomere during vegetative growth

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FYPO:0000085 - sensitive to camptothecin

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FYPO:0000088 - sensitive to hydroxyurea

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FYPO:0000267 - sensitive to ionizing radiation during vegetative growth

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FYPO:0000268 - sensitive to UV during vegetative growth

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FYPO:0002239 - shortened telomeres during vegetative growth

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