Haploid genotype - nbs1delta rad3delta

Genotype summary

Description: nbs1delta rad3delta
Organism: Schizosaccharomyces pombe (fission yeast)

Allele summary

gene	Product	Allele name	Description	Type	Expression
nbs1 (SPBC6B1.09c)	Mre11 complex BRCT domain subunit Nbs1	nbs1delta	deletion	deletion	Null
rad3 (SPBC216.05)	ATR checkpoint kinase Rad3	rad3delta	deletion	deletion	Null

Annotation

Multi-locus phenotype

FYPO:0002471 - abolished protein phosphorylation during cellular response to ionizing radiation

References:

PMID:29851556

Genes:

FYPO:0002702 - circularized chromosome

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Genes:

FYPO:0004867 - decreased histone H2A phosphorylation during cellular response to ionizing radiation

References:

PMID:29851556

Genes:

FYPO:0001355 - decreased vegetative cell population growth

References:

PMID:15964794

Genes:

FYPO:0000085 - sensitive to camptothecin

References:

PMID:21098122

Genes:

FYPO:0000267 - sensitive to ionizing radiation during vegetative growth

References:

Genes:

FYPO:0000268 - sensitive to UV during vegetative growth

References:

Genes:

FYPO:0005404 - telomeric regions absent from linear chromosomes

References:

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