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Haploid genotype - ndc80-21(T307A,E379G,L405P aa)

Genotype summary

Description
ndc80-21(T307A,E379G,L405P aa)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
ndc80 (SPBC11C11.03)Ndc80 complex subunit Ndc80ndc80-21T307A,E379G,L405Pamino_acid_mutationNot assayed or wild type

Annotation

Single locus phenotype

FYPO:0004213 - abnormal attachment of mitotic spindle microtubules to kinetochore

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FYPO:0000082 - decreased cell population growth at high temperature

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FYPO:0005300 - decreased protein localization to kinetochore during mitotic spindle assembly checkpoint signaling

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FYPO:0009057 - decreased rate of microtubule catastrophe involved in meitotic centromere clustering during meiotic prophase I

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FYPO:0002638 - increased activation of mitotic spindle assembly checkpoint

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FYPO:0001387 - loss of viability at high temperature

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FYPO:0000324 - mitotic metaphase/anaphase transition delay

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FYPO:0002688 - mitotic spindle collapse without elongation during prophase

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FYPO:0000091 - sensitive to thiabendazole

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FYPO:0004366 - syntelic kinetochore attachment during mitosis

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