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Haploid genotype - orc5-H37(L266P,P375L aa)

Genotype summary

Description
orc5-H37(L266P,P375L aa)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
orc5 (SPBC646.14c)origin recognition complex subunit Orc5orc5-H37L266P,P375Lamino_acid_mutationNot assayed or wild type

Annotation

Single locus phenotype

FYPO:0000400 - abnormal cell cycle arrest at mitotic G2/M phase transition

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FYPO:0000444 - abnormal mitotic cell cycle arrest with replicated DNA

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FYPO:0000670 - abnormal mitotic sister chromatid separation

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FYPO:0003165 - cut with abnormal chromosome segregation

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FYPO:0001324 - decreased protein level during vegetative growth

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FYPO:0005167 - decreased protein localization to chromatin at centromere inner repeat

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FYPO:0001355 - decreased vegetative cell population growth

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FYPO:0003004 - increased cellular reactive oxygen species level during vegetative growth

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FYPO:0000377 - increased frequency of apoptosis

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FYPO:0000786 - increased plasmid loss

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FYPO:0000839 - inviable elongated mononucleate aseptate cell

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FYPO:0002061 - inviable vegetative cell population

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FYPO:0001387 - loss of viability at high temperature

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FYPO:0001492 - viable elongated vegetative cell

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