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Haploid genotype - pad1-1(G54S aa)

Genotype summary

Description
pad1-1(G54S aa)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
rpn11 (SPAC31G5.13)19S proteasome regulatory subunit, ubiquitin-specific protease subunit Rpn11pad1-1G54Samino_acid_mutationNot assayed or wild type

Annotation

Single locus phenotype

FYPO:0004481 - abolished cell population growth at high temperature

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FYPO:0002568 - abolished protein localization to nuclear periphery

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FYPO:0004545 - decreased proteasomal ubiquitin-dependent protein degradation

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FYPO:0000846 - decreased protein degradation during vegetative growth

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FYPO:0002774 - increased level of ubiquitinated protein in cell during vegetative growth

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FYPO:0002303 - inviable mononucleate monoseptate vegetative cell with anucleate compartment

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FYPO:0000324 - mitotic metaphase/anaphase transition delay

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FYPO:0003027 - normal poly(A)+ mRNA export from nucleus

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FYPO:0000784 - protein mislocalized to nucleus during vegetative growth

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