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Haploid genotype - pat1-114(V155G,P219S,L291F aa)

Genotype summary

Description
pat1-114(V155G,P219S,L291F aa)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
pat1 (SPBC19C2.05)serine/threonine protein kinase Ran1/Pat1pat1-114V155G,P219S,L291Famino_acid_mutationNot assayed or wild type

Annotation

Single locus phenotype

FYPO:0004989 - abnormal meiotic centromere clustering resulting in centromere-spindle pole body colocalization during prophase

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FYPO:0000659 - abolished DNA binding

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FYPO:0000705 - abolished protein-protein interaction

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FYPO:0000445 - cell cycle arrest in mitotic G1 phase

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FYPO:0001660 - decreased cellular cAMP level

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FYPO:0003179 - decreased intragenic meiotic recombination

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FYPO:0000835 - decreased protein level

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FYPO:0002679 - decreased protein phosphorylation

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FYPO:0001152 - decreased RNA level during nitrogen starvation

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FYPO:0004990 - G2-exit meiosis with abolished premeiotic DNA replication

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FYPO:0000836 - increased protein level

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FYPO:0000572 - increased rate of shmoo formation

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FYPO:0001890 - increased RNA level

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FYPO:0000825 - increased RNA level during vegetative growth

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FYPO:0002061 - inviable vegetative cell population

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FYPO:0001886 - meiotic cell cycle entry and sporulation in haploid

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FYPO:0002043 - normal premeiotic DNA replication

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FYPO:0004083 - normal protein level

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FYPO:0000833 - normal protein level during vegetative growth

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FYPO:0000776 - normal protein phosphorylation during vegetative growth

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FYPO:0001317 - normal RNA level during vegetative growth

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FYPO:0000590 - normal sporulation

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FYPO:0001357 - normal vegetative cell population growth

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FYPO:0001112 - premature cell cycle arrest in mitotic G1 phase in response to nitrogen starvation

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FYPO:0002060 - viable vegetative cell population

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