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Haploid genotype - pcf1-ED*(Y340A,W348A aa)

Genotype summary

Description
pcf1-ED*(Y340A,W348A aa)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
pcf1 (SPBC29A10.03c)histone H3-H4 chaperone, CAF assembly factor (CAF-1) complex subunit A Pcf1pcf1-ED*Y340A,W348Aamino_acid_mutationNot assayed or wild type

Annotation

Single locus phenotype

FYPO:0007160 - abnormal DNA replication-dependent nucleosome assembly

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FYPO:0003412 - decreased chromatin silencing at centromere outer repeat

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FYPO:0007158 - decreased histone H3 binding

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FYPO:0007159 - decreased histone H4 binding

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FYPO:0004709 - increased number of Rad52 foci

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FYPO:0001571 - increased protein-protein interaction

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FYPO:0005116 - increased punctate nuclear protein localization

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