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Haploid genotype - pcf1-KER*(R147E,K150E,K154E,R161E,K168E aa)

Genotype summary

Description
pcf1-KER*(R147E,K150E,K154E,R161E,K168E aa)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
pcf1 (SPBC29A10.03c)histone H3-H4 chaperone, CAF assembly factor (CAF-1) complex subunit A Pcf1pcf1-KER*R147E,K150E,K154E,R161E,K168Eamino_acid_mutationNot assayed or wild type

Annotation

Single locus phenotype

FYPO:0007160 - abnormal DNA replication-dependent nucleosome assembly

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FYPO:0000705 - abolished protein-protein interaction

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FYPO:0003412 - decreased chromatin silencing at centromere outer repeat

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FYPO:0005018 - decreased double-stranded DNA binding

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FYPO:0002624 - decreased punctate nuclear protein localization

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FYPO:0004709 - increased number of Rad52 foci

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FYPO:0008272 - normal histone H3 binding

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FYPO:0008273 - normal histone H4 binding

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