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Haploid genotype - pcf1delta

Genotype summary

Description
pcf1delta
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
pcf1 (SPBC29A10.03c)histone H3-H4 chaperone, CAF assembly factor (CAF-1) complex subunit A Pcf1pcf1deltadeletiondeletionNull

Annotation

Single locus phenotype

FYPO:0001352 - abnormal chromatin organization during vegetative growth

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FYPO:0002346 - abnormal chromatin silencing at centromere outer repeat

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FYPO:0007160 - abnormal DNA replication-dependent nucleosome assembly

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FYPO:0000705 - abolished protein-protein interaction

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FYPO:0009053 - decreased cell population growth on glutamate nitrogen source

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FYPO:0009091 - decreased cell population growth on lysine and proline nitrogen source

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FYPO:0009092 - decreased cell population growth on lysine and serine nitrogen source

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FYPO:0009073 - decreased cell population growth on lysine nitrogen source

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FYPO:0000250 - decreased cell population growth on proline nitrogen source

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FYPO:0007562 - decreased cell population growth on serine nitrogen source

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FYPO:0002827 - decreased chromatin silencing at silent mating-type cassette

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FYPO:0006920 - decreased DNA recombination at mitotic DNA replication fork barriers

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FYPO:0005093 - decreased duration of protein phosphorylation during cellular response to hydroxyurea

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FYPO:0005094 - decreased duration of S-phase DNA damage checkpoint during cellular response to hydroxyurea

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FYPO:0007478 - decreased epigenetic heterochromatin inheritance

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FYPO:0003096 - decreased histone H3-K9 methylation at centromere outer repeat during vegetative growth

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FYPO:0003571 - decreased histone H3-K9 methylation at silent mating-type cassette during vegetative growth

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FYPO:0000708 - decreased mating efficiency

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FYPO:0000470 - decreased mating type switching

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FYPO:0001324 - decreased protein level during vegetative growth

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FYPO:0003573 - decreased protein localization to heterochromatin at silent mating-type cassette

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FYPO:0005338 - decreased protein localization to nucleus during cellular response to hydroxyurea

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FYPO:0001514 - decreased protein localization to nucleus during vegetative growth

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FYPO:0002386 - decreased protein localization to pericentric heterochromatin at centromere outer repeat region

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FYPO:0002624 - decreased punctate nuclear protein localization

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FYPO:0004709 - increased number of Rad52 foci

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FYPO:0004026 - loss of template switch-mediated chromosomal rearrangement during replication fork processing

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FYPO:0006518 - loss of viability in G0

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FYPO:0001000 - normal cell cycle arrest in mitotic G1 phase during nitrogen starvation

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FYPO:0003555 - normal chromatin silencing at subtelomere

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FYPO:0007479 - normal epigenetic heterochromatin inheritance

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FYPO:0007553 - normal G1 to G0 transition

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FYPO:0000969 - normal growth during cellular response to UV

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FYPO:0003906 - normal growth on bleomycin

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FYPO:0001690 - normal growth on camptothecin

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FYPO:0001164 - normal growth on glucose carbon source

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FYPO:0000963 - normal growth on hydroxyurea

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FYPO:0000957 - normal growth on methyl methanesulfonate

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FYPO:0003574 - normal histone H3-K14 acetylation at centromere outer repeat during vegetative growth

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FYPO:0003575 - normal histone H3-K9 acetylation at centromere outer repeat during vegetative growth

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FYPO:0005340 - normal histone H4 deacetylation during cellular response to hydroxyurea

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FYPO:0000478 - normal meiosis

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FYPO:0003246 - normal mitotic S phase progression

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FYPO:0000833 - normal protein level during vegetative growth

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FYPO:0003576 - normal protein localization to subtelomeric heterochromatin

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FYPO:0001357 - normal vegetative cell population growth

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FYPO:0000763 - resistance to cadmium

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FYPO:0002693 - resistance to diamide

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FYPO:0009038 - resistance to egtazic acid

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FYPO:0009034 - resistance to ethylenediaminetetraacetic acid

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FYPO:0009043 - resistance to potassium chloride and sodium dodecyl sulfate

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FYPO:0003383 - resistance to tert-butyl hydroperoxide

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FYPO:0007933 - sensitive to 2,2′-dipyridyl

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FYPO:0001097 - sensitive to amitrole

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FYPO:0009067 - sensitive to amorolfine

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FYPO:0009069 - sensitive to ciclopirox olamine

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FYPO:0000088 - sensitive to hydroxyurea

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FYPO:0000089 - sensitive to methyl methanesulfonate

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FYPO:0007924 - sensitive to potassium chloride and sodium dodecyl sulfate

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FYPO:0002328 - sensitive to terbinafine

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FYPO:0003656 - sensitive to vanadate

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FYPO:0002060 - viable vegetative cell population

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FYPO:0002177 - viable vegetative cell with normal cell morphology

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