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Haploid genotype - pfh1-L430V(aa)

Genotype summary

Description
pfh1-L430V(aa)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
pfh1 (SPBC887.14c)mitochondrial 5' to 3' DNA helicase Pif1/Pfh1 OR nuclear 5' to 3' DNA helicase Pif1/Pfh1pfh1-L430VL430Vamino_acid_mutationNot assayed or wild type

Annotation

Single locus phenotype

FYPO:0006651 - abolished ATP-dependent protein-DNA complex displacement activity

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FYPO:0006648 - decreased 5'-3' DNA/RNA helicase activity

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FYPO:0006656 - decreased G-quadruplex DNA unwinding

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FYPO:0006652 - increased DNA/DNA annealing activity

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FYPO:0004300 - normal ATPase activity

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FYPO:0006653 - normal flap-structured DNA binding

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FYPO:0006654 - normal G-quadruplex DNA binding

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