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Haploid genotype - pku70delta rad50delta

Genotype summary

Description
pku70delta rad50delta
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
pku70 (SPCC126.02c)Ku70 (human XRCC6 ortholog) Pku70pku70deltadeletiondeletionNull
rad50 (SPAC1556.01c)DNA repair protein Rad50rad50deltadeletiondeletionNull

Annotation

Multi-locus phenotype

FYPO:0006323 - loss of viability following replication fork stalling

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FYPO:0006319 - normal extent of DNA resection during replication fork processing

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FYPO:0000969 - normal growth during cellular response to UV

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FYPO:0006320 - normal replication slippage during replication fork processing

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FYPO:0000088 - sensitive to hydroxyurea

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FYPO:0000267 - sensitive to ionizing radiation during vegetative growth

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FYPO:0000089 - sensitive to methyl methanesulfonate

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