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Haploid genotype - pku80delta

Genotype summary

Description
pku80delta
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
pku80 (SPBC543.03c)Ku domain helicase (human XRCC5 ortholog) Pku80pku80deltadeletiondeletionNull

Annotation

Single locus phenotype

FYPO:0002254 - abnormal telomere morphology during vegetative growth

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FYPO:0005459 - abolished double-strand break repair via nonhomologous end joining

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FYPO:0009099 - decreased cell population growth on mannitol carbon source

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FYPO:0006687 - decreased DNA double-strand break processing during double-strand break repair via homologous recombination

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FYPO:0000470 - decreased mating type switching

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FYPO:0007261 - decreased telomere tethering at nuclear periphery during vegetative growth

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FYPO:0005545 - decreased Tf body formation

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FYPO:0007270 - decreased Tf body tethering to centromere

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FYPO:0001355 - decreased vegetative cell population growth

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FYPO:0009052 - increased cell population growth on glutamate nitrogen source

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FYPO:0009094 - increased cell population growth on lysine and proline nitrogen source

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FYPO:0005262 - increased cell population growth on maltose carbon source

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FYPO:0005407 - increased DNA recombination at telomere during nitrogen starvation

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FYPO:0005405 - increased DNA recombination at telomere during vegetative growth

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FYPO:0005406 - increased DNA recombination at telomere following meiotic cell cycle

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FYPO:0002573 - increased number of Ssb1 foci

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FYPO:0004656 - increased protein localization to telomere during vegetative growth

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FYPO:0006518 - loss of viability in G0

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FYPO:0000245 - loss of viability in stationary phase

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FYPO:0001870 - normal centromere clustering at nuclear periphery during vegetative growth

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FYPO:0002335 - normal chromatin silencing

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FYPO:0007553 - normal G1 to G0 transition

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FYPO:0002169 - normal growth during cellular response to gamma radiation

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FYPO:0004229 - normal growth during cellular response to ionizing radiation

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FYPO:0000969 - normal growth during cellular response to UV

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FYPO:0001690 - normal growth on camptothecin

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FYPO:0001164 - normal growth on glucose carbon source

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FYPO:0000963 - normal growth on hydroxyurea

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FYPO:0000957 - normal growth on methyl methanesulfonate

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FYPO:0007269 - normal interphase mitotic telomere clustering during vegetative growth

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FYPO:0002554 - normal protein localization to double-strand break site

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FYPO:0001317 - normal RNA level during vegetative growth

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FYPO:0001357 - normal vegetative cell population growth

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FYPO:0009041 - resistance to 2,2′-dipyridyl

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FYPO:0009030 - resistance to amitrole

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FYPO:0000764 - resistance to cycloheximide

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FYPO:0009038 - resistance to egtazic acid

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FYPO:0009034 - resistance to ethylenediaminetetraacetic acid

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FYPO:0009087 - resistance to magnesium chloride and sodium dodecyl sulfate

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FYPO:0005266 - resistance to sodium dodecyl sulfate

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FYPO:0000830 - resistance to vanadate

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FYPO:0001098 - sensitive to 4-nitroquinoline N-oxide

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FYPO:0000096 - sensitive to cadmium

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FYPO:0001188 - sensitive to Calcofluor White

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FYPO:0000104 - sensitive to cycloheximide

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FYPO:0000799 - sensitive to diamide

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FYPO:0007931 - sensitive to egtazic acid

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FYPO:0000842 - sensitive to ethanol during vegetative growth

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FYPO:0000087 - sensitive to hydrogen peroxide

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FYPO:0000088 - sensitive to hydroxyurea

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FYPO:0001719 - sensitive to lithium

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FYPO:0009084 - sensitive to lithium chloride and methyl methanesulfonate

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FYPO:0009086 - sensitive to lithium chloride and sodium dodecyl sulfate

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FYPO:0009088 - sensitive to magnesium chloride and sodium dodecyl sulfate

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FYPO:0000089 - sensitive to methyl methanesulfonate

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FYPO:0002344 - sensitive to phleomycin

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FYPO:0001214 - sensitive to potassium chloride

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FYPO:0009082 - sensitive to potassium chloride and methyl methanesulfonate

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FYPO:0007924 - sensitive to potassium chloride and sodium dodecyl sulfate

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FYPO:0005889 - sensitive to sodium chloride

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FYPO:0009090 - sensitive to sodium chloride and sodium dodecyl sulfate

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FYPO:0001457 - sensitive to tunicamycin

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FYPO:0006011 - shmoo formation at cell side

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FYPO:0002239 - shortened telomeres during vegetative growth

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FYPO:0003929 - spores sensitive to ionizing radiation

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FYPO:0002060 - viable vegetative cell population

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FYPO:0002177 - viable vegetative cell with normal cell morphology

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