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Haploid genotype - pob3delta

Genotype summary

Description
pob3delta
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
pob3 (SPBC609.05)histone H2A-H2B chaperone, FACT complex subunit Pob3pob3deltadeletiondeletionNull

Annotation

Single locus phenotype

FYPO:0000164 - abnormal cell separation after cytokinesis

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FYPO:0000854 - abnormal nucleosome positioning in euchromatin

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FYPO:0007376 - abolished epigenetic heterochromatin inheritance

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FYPO:0000082 - decreased cell population growth at high temperature

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FYPO:0000080 - decreased cell population growth at low temperature

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FYPO:0003217 - decreased chromatin silencing at centromere central core

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FYPO:0003411 - decreased chromatin silencing at centromere inner repeat

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FYPO:0006993 - decreased chromatin silencing at centromere otr1R

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FYPO:0003412 - decreased chromatin silencing at centromere outer repeat

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FYPO:0002827 - decreased chromatin silencing at silent mating-type cassette

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FYPO:0004604 - decreased chromatin silencing at subtelomere

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FYPO:0007478 - decreased epigenetic heterochromatin inheritance

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FYPO:0005222 - decreased histone H3 localization to chromatin at protein coding gene

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FYPO:0004137 - decreased histone H3-K9 dimethylation at subtelomeric heterochromatin during vegetative growth

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FYPO:0008185 - decreased histone H3-K9 trimethylation at centromere central core during vegetative growth

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FYPO:0000883 - decreased histone H3-K9 trimethylation at centromere during vegetative growth

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FYPO:0005845 - decreased histone H3-K9 trimethylation at silent mating-type cassette during vegetative growth

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FYPO:0004578 - decreased level of histone H3 in cell

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FYPO:0004491 - decreased nucleosome occupancy

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FYPO:0007837 - decreased nucleosome occupancy at subtelomere

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FYPO:0001324 - decreased protein level during vegetative growth

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FYPO:0006599 - decreased protein localization to centromeric chromatin during vegetative growth

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FYPO:0002387 - decreased protein localization to subtelomeric heterochromatin during vegetative growth

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FYPO:0001117 - decreased RNA level during vegetative growth

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FYPO:0005849 - decreased spatial extent of heterochromatin assembly

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FYPO:0005528 - decreased subtelomeric chromatin knob formation

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FYPO:0002019 - elongated telomeres during vegetative growth

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FYPO:0002913 - increased antisense RNA transcription

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FYPO:0005372 - increased circular minichromosome loss during vegetative growth

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FYPO:0007892 - increased histone exchange at subtelomeric heterochromatin

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FYPO:0007895 - increased histone H2B-K119 ubiquitination at pericentromeric heterochromatin during vegetative growth

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FYPO:0007894 - increased histone H2B-K119 ubiquitination at subtelomeric heterochromatin during vegetative growth

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FYPO:0005371 - increased linear minichromosome loss during vegetative growth

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FYPO:0003033 - increased RNA level during glucose starvation

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FYPO:0000825 - increased RNA level during vegetative growth

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FYPO:0005917 - increased subtelomeric heterochromatin RNA level

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FYPO:0001309 - increased viability in stationary phase

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FYPO:0000228 - lagging mitotic chromosomes

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FYPO:0006518 - loss of viability in G0

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FYPO:0008265 - normal chromatin silencing at rDNA

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FYPO:0003555 - normal chromatin silencing at subtelomere

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FYPO:0007553 - normal G1 to G0 transition

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FYPO:0001164 - normal growth on glucose carbon source

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FYPO:0004743 - normal histone H3-K9 dimethylation at centromere outer repeat during vegetative growth

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FYPO:0004314 - normal protein localization to CENP-A containing chromatin

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FYPO:0001357 - normal vegetative cell population growth

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FYPO:0007834 - protein displaced from 5' end to 3' end of RNA polymerase II-transcribed genes

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FYPO:0000764 - resistance to cycloheximide

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FYPO:0009038 - resistance to egtazic acid

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FYPO:0009085 - resistance to lithium chloride and sodium dodecyl sulfate

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FYPO:0009043 - resistance to potassium chloride and sodium dodecyl sulfate

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FYPO:0003383 - resistance to tert-butyl hydroperoxide

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FYPO:0004325 - sensitive to 5-fluorouracil

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FYPO:0000084 - sensitive to 6-azauracil

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FYPO:0000096 - sensitive to cadmium

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FYPO:0000085 - sensitive to camptothecin

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FYPO:0000799 - sensitive to diamide

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FYPO:0000088 - sensitive to hydroxyurea

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FYPO:0001719 - sensitive to lithium

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FYPO:0000089 - sensitive to methyl methanesulfonate

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FYPO:0000091 - sensitive to thiabendazole

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FYPO:0000268 - sensitive to UV during vegetative growth

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FYPO:0002060 - viable vegetative cell population

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FYPO:0001510 - viable vegetative cell, abnormal cell shape, normal cell size

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