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Haploid genotype - pof8delta

Genotype summary

Description
pof8delta
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
pof8 (SPAC17G6.17)LARP7 family RNA-binding protein Pof8/Lar7pof8deltadeletiondeletionNull

Annotation

Single locus phenotype

FYPO:0007394 - abnormal RNA structure

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FYPO:0008112 - abnormal U6 snRNP assembly

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FYPO:0000705 - abolished protein-protein interaction

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FYPO:0002133 - abolished protein-RNA interaction

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FYPO:0006466 - decreased mature ncRNA level

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FYPO:0000835 - decreased protein level

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FYPO:0003803 - decreased protein localization to telomere

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FYPO:0001645 - decreased protein-protein interaction

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FYPO:0002134 - decreased protein-RNA interaction

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FYPO:0000826 - decreased RNA level

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FYPO:0005540 - decreased telomerase RNA reverse transcriptase activity

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FYPO:0006848 - decreased total RNA level during vegetative growth

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FYPO:0008110 - decreased U6 2'-O-snRNA methylation at residue A64

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FYPO:0007845 - increased rate of RNA catabolic process during vegetative growth

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FYPO:0002908 - increased transcription at telomere during vegetative growth

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FYPO:0000245 - loss of viability in stationary phase

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FYPO:0004083 - normal protein level

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FYPO:0002887 - normal protein localization to telomere during vegetative growth

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FYPO:0002357 - normal protein-RNA interaction

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FYPO:0005538 - normal telomere-telomerase complex assembly

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FYPO:0003107 - progressively shortening telomeres during vegetative growth

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FYPO:0000763 - resistance to cadmium

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FYPO:0001034 - resistance to tunicamycin

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FYPO:0007808 - resistance to valproic acid

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FYPO:0000830 - resistance to vanadate

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FYPO:0000097 - sensitive to caffeine during vegetative growth

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FYPO:0000799 - sensitive to diamide

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FYPO:0000088 - sensitive to hydroxyurea

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FYPO:0009071 - sensitive to itraconazole

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FYPO:0000089 - sensitive to methyl methanesulfonate

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FYPO:0000797 - sensitive to tert-butyl hydroperoxide

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FYPO:0002239 - shortened telomeres during vegetative growth

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FYPO:0003106 - stable shortened telomeres during vegetative growth

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FYPO:0002060 - viable vegetative cell population

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FYPO:0002177 - viable vegetative cell with normal cell morphology

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