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Haploid genotype - prp10-1(A1050V,S1058F aa)

Genotype summary

Description
prp10-1(A1050V,S1058F aa)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
prp10 (SPAC27F1.09c)U2 snRNP-associated protein SF3B1prp10-1A1050V,S1058Famino_acid_mutationNot assayed or wild type

Annotation

Single locus phenotype

FYPO:0003602 - abolished mRNA splicing, via spliceosome

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FYPO:0000082 - decreased cell population growth at high temperature

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FYPO:0004201 - decreased centromeric outer repeat transcript-derived siRNA level

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FYPO:0003412 - decreased chromatin silencing at centromere outer repeat

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FYPO:0003096 - decreased histone H3-K9 methylation at centromere outer repeat during vegetative growth

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FYPO:0003029 - decreased mRNA splicing, via spliceosome

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FYPO:0006599 - decreased protein localization to centromeric chromatin during vegetative growth

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FYPO:0003041 - decreased snRNA splicing

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FYPO:0000220 - increased centromeric outer repeat transcript level

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FYPO:0001908 - increased pre-mRNA level

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FYPO:0002107 - inviable stubby vegetative cell

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FYPO:0003619 - normal mRNA splicing, via spliceosome

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FYPO:0000091 - sensitive to thiabendazole

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