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Haploid genotype - prp2-2(T259I aa)

Genotype summary

Description
prp2-2(T259I aa)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
prp2 (SPBC146.07)U2 small nuclear RNA auxiliary factor small subunit, U2AF-59prp2-2T259Iamino_acid_mutationNot assayed or wild type

Annotation

Single locus phenotype

FYPO:0000444 - abnormal mitotic cell cycle arrest with replicated DNA

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FYPO:0000062 - abnormal nuclear morphology during vegetative growth

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FYPO:0003602 - abolished mRNA splicing, via spliceosome

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FYPO:0003630 - abolished U2-type prespliceosome assembly

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FYPO:0003629 - abolished U2/U5/U6 snRNP complex assembly

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FYPO:0003165 - cut with abnormal chromosome segregation

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FYPO:0000082 - decreased cell population growth at high temperature

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FYPO:0003029 - decreased mRNA splicing, via spliceosome

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FYPO:0001645 - decreased protein-protein interaction

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FYPO:0003041 - decreased snRNA splicing

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FYPO:0001355 - decreased vegetative cell population growth

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FYPO:0008113 - increased intron retention

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FYPO:0001908 - increased pre-mRNA level

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FYPO:0002303 - inviable mononucleate monoseptate vegetative cell with anucleate compartment

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FYPO:0002107 - inviable stubby vegetative cell

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FYPO:0003166 - monoseptate vegetative cell with binucleate and anucleate compartments

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FYPO:0000091 - sensitive to thiabendazole

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FYPO:0003095 - viable elongated vegetative cell, with progressive elongation

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