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Haploid genotype - rad11-D223Y(aa)

Genotype summary

Description
rad11-D223Y(aa)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
ssb1 (SPBC660.13c)DNA replication factor A subunit Ssb1rad11-D223YD223Yamino_acid_mutationNot assayed or wild type

Annotation

Single locus phenotype

FYPO:0004845 - abnormal mitotic DNA replication lagging strand elongation at telomere

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FYPO:0001324 - decreased protein level during vegetative growth

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FYPO:0002387 - decreased protein localization to subtelomeric heterochromatin during vegetative growth

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FYPO:0002897 - decreased protein phosphorylation during cellular response to DNA damage

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FYPO:0002098 - decreased protein phosphorylation during cellular response to hydroxyurea

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FYPO:0002134 - decreased protein-RNA interaction

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FYPO:0009109 - decreased vegetative cell population growth after short incubation in hydroxyurea

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FYPO:0005649 - increased duration of protein localization to telomere

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FYPO:0004846 - increased number of Rad52 foci at telomeres

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FYPO:0003010 - increased protein localization to subtelomeric heterochromatin during vegetative growth

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FYPO:0004656 - increased protein localization to telomere during vegetative growth

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FYPO:0001038 - increased protein phosphorylation during vegetative growth

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FYPO:0001929 - normal cell cycle regulation during cellular response to hydroxyurea

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FYPO:0004437 - normal mitotic recombination frequency

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FYPO:0002887 - normal protein localization to telomere during vegetative growth

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FYPO:0002099 - normal protein phosphorylation during cellular response to hydroxyurea

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FYPO:0005445 - normal telomere 3' overhang length during vegetative growth

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FYPO:0001357 - normal vegetative cell population growth

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FYPO:0000088 - sensitive to hydroxyurea

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FYPO:0000267 - sensitive to ionizing radiation during vegetative growth

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FYPO:0000089 - sensitive to methyl methanesulfonate

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FYPO:0000268 - sensitive to UV during vegetative growth

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FYPO:0002239 - shortened telomeres during vegetative growth

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FYPO:0003106 - stable shortened telomeres during vegetative growth

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