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Haploid genotype - rad12-502(T543I aa)

Genotype summary

Description
rad12-502(T543I aa)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
rqh1 (SPAC2G11.12)RecQ type DNA helicase Rqh1rad12-502T543Iamino_acid_mutationNot assayed or wild type

Annotation

Single locus phenotype

FYPO:0002101 - abolished 3'-5' DNA helicase activity

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FYPO:0004029 - abolished 5' deoxyribonuclease (pyrimidine dimer) activity

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FYPO:0004031 - decreased UV-damage excision repair

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FYPO:0005704 - loss of viability following cellular response to hydroxyurea

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FYPO:0007142 - loss of viability following cellular response to ionizing radiation

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FYPO:0005705 - loss of viability following cellular response to UV

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FYPO:0002169 - normal growth during cellular response to gamma radiation

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FYPO:0004404 - normal growth on JM216

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FYPO:0004410 - normal growth on tetraplatin

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FYPO:0004408 - normal growth on triplatin tetranitrate

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FYPO:0000833 - normal protein level during vegetative growth

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FYPO:0000102 - sensitive to cisplatin

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FYPO:0000088 - sensitive to hydroxyurea

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FYPO:0000267 - sensitive to ionizing radiation during vegetative growth

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FYPO:0004405 - sensitive to JM335

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FYPO:0002345 - sensitive to oxaliplatin

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FYPO:0000268 - sensitive to UV during vegetative growth

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FYPO:0001492 - viable elongated vegetative cell

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