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Haploid genotype - rad17delta

Genotype summary

Description
rad17delta
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
rad17 (SPAC14C4.13)RFC related checkpoint protein Rad17rad17deltadeletiondeletionNull

Annotation

Single locus phenotype

FYPO:0001931 - abnormal mitotic cell cycle regulation during cellular response to gamma radiation

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FYPO:0005179 - abnormal mitotic cell cycle regulation during cellular response to UV during mitotic G1 phase

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FYPO:0002711 - abnormal nuclear separation after meiosis

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FYPO:0003088 - abnormal replication fork arrest

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FYPO:0003486 - abolished protein localization to double-strand break site

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FYPO:0001424 - abolished protein localization to nucleus during vegetative growth

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FYPO:0003165 - cut with abnormal chromosome segregation

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FYPO:0000251 - decreased cell population growth on galactose carbon source

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FYPO:0009053 - decreased cell population growth on glutamate nitrogen source

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FYPO:0009091 - decreased cell population growth on lysine and proline nitrogen source

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FYPO:0009092 - decreased cell population growth on lysine and serine nitrogen source

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FYPO:0009073 - decreased cell population growth on lysine nitrogen source

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FYPO:0000250 - decreased cell population growth on proline nitrogen source

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FYPO:0007562 - decreased cell population growth on serine nitrogen source

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FYPO:0002577 - decreased chromatin binding

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FYPO:0000185 - decreased gene conversion during vegetative growth

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FYPO:0002485 - decreased intergenic meiotic recombination

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FYPO:0003179 - decreased intragenic meiotic recombination

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FYPO:0002097 - decreased protein kinase activity during cellular response to hydroxyurea

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FYPO:0003143 - decreased protein level during cellular response to methyl methanesulfonate

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FYPO:0002098 - decreased protein phosphorylation during cellular response to hydroxyurea

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FYPO:0001838 - decreased protein phosphorylation during vegetative growth

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FYPO:0003142 - decreased RNA level during cellular response to methyl methanesulfonate

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FYPO:0003034 - decreased RNA level during cellular response to UV

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FYPO:0003004 - increased cellular reactive oxygen species level during vegetative growth

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FYPO:0000377 - increased frequency of apoptosis

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FYPO:0001840 - increased minichromosome loss during vegetative growth

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FYPO:0000972 - increased number of Rad52 foci during vegetative growth

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FYPO:0002096 - increased protein phosphorylation during cellular response to hydroxyurea

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FYPO:0006518 - loss of viability in G0

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FYPO:0000378 - normal apoptosis

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FYPO:0003118 - normal cellular reactive oxygen species level during vegetative growth

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FYPO:0003086 - normal chromatin binding

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FYPO:0004286 - normal double-strand break repair via nonhomologous end joining

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FYPO:0007553 - normal G1 to G0 transition

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FYPO:0003174 - normal nucleotide-excision repair during cellular response to UV

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FYPO:0005181 - normal protein degradation during cellular response to UV

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FYPO:0005236 - normal protein localization to chromatin at stalled replication fork

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FYPO:0000838 - normal protein localization to nucleus during vegetative growth

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FYPO:0003576 - normal protein localization to subtelomeric heterochromatin

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FYPO:0005614 - normal protein phosphorylation during cellular response to bleomycin

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FYPO:0002099 - normal protein phosphorylation during cellular response to hydroxyurea

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FYPO:0003131 - normal protein phosphorylation during cellular response to ionizing radiation

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FYPO:0005395 - normal protein phosphorylation during cellular response to methyl methanesulfonate

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FYPO:0000703 - normal protein-protein interaction

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FYPO:0003035 - normal RNA level during cellular response to UV

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FYPO:0004993 - normal spore germination frequency

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FYPO:0000764 - resistance to cycloheximide

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FYPO:0009043 - resistance to potassium chloride and sodium dodecyl sulfate

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FYPO:0003383 - resistance to tert-butyl hydroperoxide

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FYPO:0000830 - resistance to vanadate

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FYPO:0007933 - sensitive to 2,2′-dipyridyl

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FYPO:0001098 - sensitive to 4-nitroquinoline N-oxide

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FYPO:0001097 - sensitive to amitrole

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FYPO:0009067 - sensitive to amorolfine

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FYPO:0000095 - sensitive to bleomycin

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FYPO:0000085 - sensitive to camptothecin

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FYPO:0003384 - sensitive to chromium

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FYPO:0009069 - sensitive to ciclopirox olamine

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FYPO:0000102 - sensitive to cisplatin

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FYPO:0000088 - sensitive to hydroxyurea

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FYPO:0000267 - sensitive to ionizing radiation during vegetative growth

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FYPO:0009071 - sensitive to itraconazole

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FYPO:0009084 - sensitive to lithium chloride and methyl methanesulfonate

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FYPO:0009088 - sensitive to magnesium chloride and sodium dodecyl sulfate

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FYPO:0000089 - sensitive to methyl methanesulfonate

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FYPO:0009082 - sensitive to potassium chloride and methyl methanesulfonate

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FYPO:0002328 - sensitive to terbinafine

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FYPO:0000268 - sensitive to UV during vegetative growth

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FYPO:0009064 - sensitive to X-rays and rapamycin during vegetative growth.

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FYPO:0009063 - sensitive to X-rays during vegetative growth

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FYPO:0002239 - shortened telomeres during vegetative growth

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FYPO:0002060 - viable vegetative cell population

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FYPO:0002177 - viable vegetative cell with normal cell morphology

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