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Haploid genotype - rad3delta tel1delta

Genotype summary

Description
rad3delta tel1delta
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
rad3 (SPBC216.05)ATR checkpoint kinase Rad3rad3deltadeletiondeletionNull
tel1 (SPCC23B6.03c)ATM checkpoint kinasetel1deltadeletiondeletionNull

Annotation

Multi-locus phenotype

FYPO:0002472 - abolished histone H2A phosphorylation during cellular response to ionizing radiation

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FYPO:0002597 - abolished histone H2A phosphorylation during vegetative growth

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FYPO:0001508 - abolished protein localization to chromatin during vegetative growth

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FYPO:0005616 - abolished protein phosphorylation during cellular response to bleomycin

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FYPO:0004550 - abolished protein phosphorylation during cellular response to hydroxyurea

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FYPO:0002702 - circularized chromosome

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FYPO:0004869 - decreased number of Crb2 foci during cellular response to ionizing radiation

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FYPO:0005577 - decreased protein phosphorylation during meiotic cell cycle

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FYPO:0001838 - decreased protein phosphorylation during vegetative growth

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FYPO:0001355 - decreased vegetative cell population growth

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FYPO:0004656 - increased protein localization to telomere during vegetative growth

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FYPO:0003129 - loss of punctate nuclear protein localization during cellular response to ionizing radiation

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FYPO:0000245 - loss of viability in stationary phase

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FYPO:0004286 - normal double-strand break repair via nonhomologous end joining

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FYPO:0004692 - normal protein localization to mitotic spindle midzone

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FYPO:0002099 - normal protein phosphorylation during cellular response to hydroxyurea

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FYPO:0005395 - normal protein phosphorylation during cellular response to methyl methanesulfonate

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FYPO:0005394 - progressively decreasing vegetative cell population growth rate followed by return to normal growth rate

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FYPO:0000085 - sensitive to camptothecin

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