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Haploid genotype - rad9-T225C(aa)

Genotype summary

Description
rad9-T225C(aa)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
rad9 (SPAC664.07c)checkpoint clamp complex protein Rad9rad9-T225CT225Camino_acid_mutationNot assayed or wild type

Annotation

Single locus phenotype

FYPO:0001931 - abnormal mitotic cell cycle regulation during cellular response to gamma radiation

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FYPO:0002471 - abolished protein phosphorylation during cellular response to ionizing radiation

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FYPO:0000705 - abolished protein-protein interaction

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FYPO:0004464 - decreased protein phosphorylation during cellular response to camptothecin

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FYPO:0004436 - increased error-prone translesion synthesis

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FYPO:0000473 - increased mitotic recombination

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FYPO:0004466 - increased number of Rad52 foci during cellular response to camptothecin

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FYPO:0000256 - mutator

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FYPO:0001690 - normal growth on camptothecin

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FYPO:0001705 - normal mitotic DNA damage checkpoint

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FYPO:0002099 - normal protein phosphorylation during cellular response to hydroxyurea

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FYPO:0000085 - sensitive to camptothecin

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FYPO:0000088 - sensitive to hydroxyurea

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FYPO:0000089 - sensitive to methyl methanesulfonate

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