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Haploid genotype - raf1-R576H(aa)[Knockdown]

Genotype summary

Description
raf1-R576H(aa)[Knockdown]
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
raf1 (SPCC613.12c)CLRC ubiquitin ligase complex WD repeat subunit Raf1/Dos1raf1-R576HR576Hamino_acid_mutationKnockdown

Annotation

Single locus phenotype

FYPO:0002827 - decreased chromatin silencing at silent mating-type cassette

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FYPO:0005845 - decreased histone H3-K9 trimethylation at silent mating-type cassette during vegetative growth

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FYPO:0004577 - decreased histone H3-K9 trimethylation at subtelomeric heterochromatin during vegetative growth

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FYPO:0003573 - decreased protein localization to heterochromatin at silent mating-type cassette

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FYPO:0001645 - decreased protein-protein interaction

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FYPO:0008070 - normal histone H3-K9 methylation at centromere during vegetative growth

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