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Haploid genotype - raf1delta

Genotype summary

Description
raf1delta
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
raf1 (SPCC613.12c)CLRC ubiquitin ligase complex WD repeat subunit Raf1/Dos1raf1deltadeletiondeletionNull

Annotation

Single locus phenotype

FYPO:0000468 - abnormal mating type switching

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FYPO:0003659 - abnormal mating type switching resulting in duplication or deletion in mating-type region

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FYPO:0007336 - abolished chromatin silencing at silent mating-type cassette

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FYPO:0005850 - abolished protein localization to heterochromatin at centromere outer repeat

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FYPO:0001978 - bent mitotic spindle

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FYPO:0009053 - decreased cell population growth on glutamate nitrogen source

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FYPO:0000684 - decreased cell population growth on glycerol carbon source

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FYPO:0009091 - decreased cell population growth on lysine and proline nitrogen source

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FYPO:0009092 - decreased cell population growth on lysine and serine nitrogen source

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FYPO:0009073 - decreased cell population growth on lysine nitrogen source

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FYPO:0002924 - decreased cell population growth on maltose carbon source

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FYPO:0007562 - decreased cell population growth on serine nitrogen source

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FYPO:0001176 - decreased cell population growth on sucrose carbon source

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FYPO:0002834 - decreased chromatin silencing at centromere

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FYPO:0003412 - decreased chromatin silencing at centromere outer repeat

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FYPO:0002827 - decreased chromatin silencing at silent mating-type cassette

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FYPO:0004604 - decreased chromatin silencing at subtelomere

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FYPO:0003352 - decreased DNA double-strand break formation at mating-type locus

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FYPO:0002355 - decreased histone H3-K9 dimethylation at silent mating-type cassette during vegetative growth

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FYPO:0000708 - decreased mating efficiency

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FYPO:0000470 - decreased mating type switching

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FYPO:0004904 - decreased protein localization to centromere central core during vegetative growth

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FYPO:0002386 - decreased protein localization to pericentric heterochromatin at centromere outer repeat region

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FYPO:0005261 - increased cell population growth on galactose carbon source

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FYPO:0006353 - increased centromere central core transcript level

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FYPO:0002836 - increased centromeric outer repeat transcript-derived siRNA level

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FYPO:0005063 - increased histone H3-K4 methylation at mating type locus during vegetative growth

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FYPO:0001840 - increased minichromosome loss during vegetative growth

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FYPO:0001327 - increased protein level during vegetative growth

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FYPO:0004909 - loss of punctate nuclear protein localization, with protein distributed in nucleus

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FYPO:0006518 - loss of viability in G0

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FYPO:0000245 - loss of viability in stationary phase

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FYPO:0002837 - normal centromeric outer repeat transcript-derived siRNA level

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FYPO:0007553 - normal G1 to G0 transition

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FYPO:0000969 - normal growth during cellular response to UV

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FYPO:0001690 - normal growth on camptothecin

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FYPO:0000963 - normal growth on hydroxyurea

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FYPO:0000957 - normal growth on methyl methanesulfonate

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FYPO:0000833 - normal protein level during vegetative growth

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FYPO:0002574 - normal protein localization to centromere during vegetative growth

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FYPO:0001357 - normal vegetative cell population growth

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FYPO:0002634 - resistance to cobalt

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FYPO:0009040 - resistance to tea tree oil

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FYPO:0007933 - sensitive to 2,2′-dipyridyl

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FYPO:0004325 - sensitive to 5-fluorouracil

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FYPO:0001097 - sensitive to amitrole

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FYPO:0009067 - sensitive to amorolfine

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FYPO:0000095 - sensitive to bleomycin

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FYPO:0000097 - sensitive to caffeine during vegetative growth

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FYPO:0009069 - sensitive to ciclopirox olamine

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FYPO:0000104 - sensitive to cycloheximide

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FYPO:0000799 - sensitive to diamide

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FYPO:0007931 - sensitive to egtazic acid

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FYPO:0000842 - sensitive to ethanol during vegetative growth

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FYPO:0007928 - sensitive to ethylenediaminetetraacetic acid

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FYPO:0000785 - sensitive to formamide

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FYPO:0000087 - sensitive to hydrogen peroxide

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FYPO:0000088 - sensitive to hydroxyurea

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FYPO:0009071 - sensitive to itraconazole

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FYPO:0001719 - sensitive to lithium

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FYPO:0009086 - sensitive to lithium chloride and sodium dodecyl sulfate

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FYPO:0006836 - sensitive to magnesium chloride

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FYPO:0009088 - sensitive to magnesium chloride and sodium dodecyl sulfate

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FYPO:0000089 - sensitive to methyl methanesulfonate

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FYPO:0001214 - sensitive to potassium chloride

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FYPO:0009082 - sensitive to potassium chloride and methyl methanesulfonate

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FYPO:0007924 - sensitive to potassium chloride and sodium dodecyl sulfate

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FYPO:0009090 - sensitive to sodium chloride and sodium dodecyl sulfate

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FYPO:0000841 - sensitive to sodium dodecyl sulfate

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FYPO:0002328 - sensitive to terbinafine

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FYPO:0000797 - sensitive to tert-butyl hydroperoxide

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FYPO:0000091 - sensitive to thiabendazole

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FYPO:0000115 - sensitive to valproic acid

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FYPO:0003656 - sensitive to vanadate

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FYPO:0003241 - unequal mitotic sister chromatid segregation

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FYPO:0002060 - viable vegetative cell population

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FYPO:0002177 - viable vegetative cell with normal cell morphology

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