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Haploid genotype - rap1delta

Genotype summary

Description
rap1delta
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
rap1 (SPBC1778.02)shelterin complex scaffold subunit Rap1rap1deltadeletiondeletionNull

Annotation

Single locus phenotype

FYPO:0000169 - abnormal chromatin silencing at subtelomere

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FYPO:0000151 - abnormal meiotic chromosome segregation

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FYPO:0000121 - abnormal sporulation

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FYPO:0003066 - abnormal sporulation resulting in formation of ascus with fewer than four spores

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FYPO:0001894 - abnormal sporulation resulting in formation of ascus with more or fewer than four spores

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FYPO:0006366 - abolished meiotic telomere clustering

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FYPO:0002702 - circularized chromosome

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FYPO:0002907 - circularized chromosome during mitotic G1 phase

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FYPO:0009092 - decreased cell population growth on lysine and serine nitrogen source

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FYPO:0000250 - decreased cell population growth on proline nitrogen source

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FYPO:0007562 - decreased cell population growth on serine nitrogen source

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FYPO:0004604 - decreased chromatin silencing at subtelomere

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FYPO:0005937 - decreased protein localization to chromatin at late replication origin

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FYPO:0000581 - decreased spore germination frequency

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FYPO:0002019 - elongated telomeres during vegetative growth

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FYPO:0005262 - increased cell population growth on maltose carbon source

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FYPO:0000657 - increased DNA binding

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FYPO:0004575 - increased histone H3-K9 acetylation at subtelomere during vegetative growth

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FYPO:0004656 - increased protein localization to telomere during vegetative growth

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FYPO:0005917 - increased subtelomeric heterochromatin RNA level

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FYPO:0006267 - increased telomere clustering and tethering at nuclear periphery during mitotic metaphase

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FYPO:0004791 - increased telomere-nuclear envelope distance during mitotic G2 phase

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FYPO:0004573 - increased telomeric transcript level

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FYPO:0002908 - increased transcription at telomere during vegetative growth

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FYPO:0000780 - increased transcription during vegetative growth

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FYPO:0001309 - increased viability in stationary phase

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FYPO:0006518 - loss of viability in G0

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FYPO:0002141 - normal cell population growth at low temperature

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FYPO:0004742 - normal chromatin silencing at centromere outer repeat

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FYPO:0007553 - normal G1 to G0 transition

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FYPO:0001164 - normal growth on glucose carbon source

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FYPO:0000964 - normal growth on thiabendazole

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FYPO:0002620 - normal growth on trichostatin A

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FYPO:0004330 - normal mitotic telomeric DNA separation

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FYPO:0000833 - normal protein level during vegetative growth

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FYPO:0004195 - normal protein localization to telomere during meiosis

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FYPO:0002887 - normal protein localization to telomere during vegetative growth

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FYPO:0000590 - normal sporulation

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FYPO:0004579 - normal transposable element-derived small RNA level

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FYPO:0001357 - normal vegetative cell population growth

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FYPO:0006272 - premature mitotic DNA replication initiation from late origin

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FYPO:0000067 - resistance to brefeldin A

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FYPO:0000073 - resistance to caffeine

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FYPO:0000764 - resistance to cycloheximide

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FYPO:0001103 - resistance to hydrogen peroxide

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FYPO:0001583 - resistance to lithium

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FYPO:0009083 - resistance to lithium chloride and methyl methanesulfonate

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FYPO:0009085 - resistance to lithium chloride and sodium dodecyl sulfate

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FYPO:0009087 - resistance to magnesium chloride and sodium dodecyl sulfate

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FYPO:0009043 - resistance to potassium chloride and sodium dodecyl sulfate

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FYPO:0003383 - resistance to tert-butyl hydroperoxide

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FYPO:0005193 - resistance to torin1

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FYPO:0000830 - resistance to vanadate

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FYPO:0006680 - sensitive to bisphenol A

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FYPO:0009069 - sensitive to ciclopirox olamine

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FYPO:0000799 - sensitive to diamide

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FYPO:0000842 - sensitive to ethanol during vegetative growth

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FYPO:0000088 - sensitive to hydroxyurea

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FYPO:0009071 - sensitive to itraconazole

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FYPO:0000089 - sensitive to methyl methanesulfonate

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FYPO:0009082 - sensitive to potassium chloride and methyl methanesulfonate

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FYPO:0002617 - sensitive to sodium butyrate

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FYPO:0000115 - sensitive to valproic acid

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FYPO:0003656 - sensitive to vanadate

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FYPO:0002060 - viable vegetative cell population

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FYPO:0002177 - viable vegetative cell with normal cell morphology

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