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Diploid genotype - rec12delta/rec12delta

Genotype summary

Description
rec12delta/rec12delta
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

locus Product Allele name Description Type Expression
rec12 (SPAC17A5.11)DNA topoisomerase type II (DSB-forming) Rec12/Spo11rec12deltadeletiondeletionNull
rec12deltadeletiondeletionNull

Annotation

Single locus phenotype

FYPO:0004159 - abnormal homologous chromosome segregation

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FYPO:0000151 - abnormal meiotic chromosome segregation

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FYPO:0003564 - abnormal meiotic DNA double-strand break formation

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FYPO:0006315 - abolished homologous chromosome segregation

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FYPO:0008302 - abolished punctate nuclear protein localization during meiotic prophase I

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FYPO:0006160 - decreased number of Rad51 foci during meiotic prophase I

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FYPO:0000581 - decreased spore germination frequency

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FYPO:0008202 - equational sister chromatid separation at meiosis I

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FYPO:0005434 - globally decreased meiotic recombination

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FYPO:0006159 - increased protein localization to linear element

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FYPO:0002151 - inviable spore

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FYPO:0007939 - normal chromatin loop formation during meiotic prophase I

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FYPO:0002219 - normal chromosome disjunction at meiosis I

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FYPO:0002094 - normal meiotic sister chromatid cohesion

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FYPO:0004634 - normal protein level during meiosis

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FYPO:0005135 - normal protein localization to linear element

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FYPO:0007802 - short linear element

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FYPO:0005634 - sister kinetochore dissociation in meiotic metaphase I with equational sister chromatid segregation in meiosis I

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