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Haploid genotype - rfc3-1(R216W aa)

Genotype summary

Description
rfc3-1(R216W aa)
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
rfc3 (SPAC27E2.10c)DNA replication factor C complex subunit Rfc3rfc3-1R216Wamino_acid_mutationNot assayed or wild type

Annotation

Single locus phenotype

FYPO:0003489 - abnormal mitotic cell cycle regulation during cellular response to ionizing radiation

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FYPO:0005268 - abnormal mitotic cell cycle regulation during cellular response to methyl methanesulfonate

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FYPO:0004254 - abnormal mitotic cell cycle regulation during cellular response to UV

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FYPO:0001343 - abnormal mitotic DNA replication

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FYPO:0000229 - cut

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FYPO:0000082 - decreased cell population growth at high temperature

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FYPO:0004360 - decreased duration of mitotic cell cycle DNA replication checkpoint

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FYPO:0002470 - decreased protein phosphorylation during cellular response to ionizing radiation

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FYPO:0002993 - decreased protein phosphorylation during cellular response to methyl methanesulfonate

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FYPO:0004228 - decreased protein phosphorylation during cellular response to UV

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FYPO:0004372 - decreased response to mitotic G2 DNA damage checkpoint signaling

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FYPO:0002596 - increased histone H2A phosphorylation during vegetative growth

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FYPO:0004951 - increased number of Brc1 foci

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FYPO:0000972 - increased number of Rad52 foci during vegetative growth

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FYPO:0002061 - inviable vegetative cell population

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FYPO:0001387 - loss of viability at high temperature

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FYPO:0001357 - normal vegetative cell population growth

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FYPO:0000088 - sensitive to hydroxyurea

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FYPO:0000267 - sensitive to ionizing radiation during vegetative growth

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FYPO:0000089 - sensitive to methyl methanesulfonate

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FYPO:0000268 - sensitive to UV during vegetative growth

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FYPO:0003241 - unequal mitotic sister chromatid segregation

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