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Haploid genotype - rhp6+(wild type)[Overexpression]

Genotype summary

Description
rhp6+(wild type)[Overexpression]
Organism
Schizosaccharomyces pombe (fission yeast)

Allele summary

gene Product Allele name Description Type Expression
rhp6 (SPAC18B11.07c)histone H2B-K119 ubiquitin ligase complex (HULC), ubiquitin conjugating enzyme E2 subunit Rhp6/Rad6rhp6+wild typewild_typeOverexpression

Annotation

Single locus phenotype

FYPO:0000146 - abnormal chromatin silencing at centromere

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FYPO:0000156 - abnormal chromatin silencing at silent mating-type cassette

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FYPO:0000169 - abnormal chromatin silencing at subtelomere

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FYPO:0007334 - abolished chromatin silencing at centromere outer repeat

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FYPO:0003096 - decreased histone H3-K9 methylation at centromere outer repeat during vegetative growth

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FYPO:0003571 - decreased histone H3-K9 methylation at silent mating-type cassette during vegetative growth

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FYPO:0003572 - decreased histone H3-K9 methylation at subtelomeric heterochromatin during vegetative growth

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FYPO:0000883 - decreased histone H3-K9 trimethylation at centromere during vegetative growth

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FYPO:0006599 - decreased protein localization to centromeric chromatin during vegetative growth

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FYPO:0005063 - increased histone H3-K4 methylation at mating type locus during vegetative growth

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FYPO:0005062 - increased histone H3-K4 methylation at telomere during vegetative growth

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FYPO:0007844 - increased histone H3-K9 monomethylation at centromere during vegetative growth

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FYPO:0001840 - increased minichromosome loss during vegetative growth

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FYPO:0004237 - increased protein localization to heterochromatin at centromere outer repeat region

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FYPO:0007843 - normal nucleosome positioning at centromere

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FYPO:0000091 - sensitive to thiabendazole

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